Applications of digital PCR in COVID‐19 pandemic

C Tan, D Fan, N Wang, F Wang, B Wang, L Zhu, Y Guo - View, 2021 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has led to a public health
crisis and global panic. This infectious disease is caused by a novel coronavirus named …

[HTML][HTML] Analytical and clinical performance of droplet digital PCR in the detection and quantification of SARS-CoV-2

KB Kim, H Choi, GD Lee, J Lee, S Lee, Y Kim… - Molecular diagnosis & …, 2021 - Springer
Abstract Background and Objective Since the initial coronavirus disease outbreak in late
2019 (COVID-19), reverse-transcription real-time polymerase chain reaction (RT-qPCR) has …

Digital PCR applications in the SARS-CoV-2/COVID-19 era: a roadmap for future outbreaks

R Nyaruaba, C Mwaliko, D Dobnik… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global public health …

Absolute quantification of SARS-CoV-2 with Clarity Plus™ digital PCR

SYH Tan, SYM Kwek, H Low, YLJ Pang - Methods, 2022 - Elsevier
In recent years, the usage of digital polymerase chain reaction (dPCR) for various clinical
applications has increased exponentially. In this study, a dPCR assay optimized on the …

Digital PCR assay for the effective detection of COVID-19 patients with SARS-CoV-2 low viral load

Y Sun, C Ding, Q Chen, J Xie, J Yu, Y Shi… - Journal of Virological …, 2021 - Elsevier
Objective Viral nucleic acid detection by real-time reverse transcription polymerase chain
reaction (qPCR) is the current standard method for diagnosis of SARS-CoV-2 infection …

SARS‐CoV‐2 in digital era: Diagnostic techniques and importance of nucleic acid quantification with digital PCRs

N Aravind Kumar, S Aradhana, Harleen… - Reviews in Medical …, 2023 - Wiley Online Library
Studies related to clinical diagnosis and research of SARS‐CoV‐2 are important in the
current pandemic era. Although molecular biology has emphasised the importance of …

Analytical comparisons of SARS-COV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets

X Liu, J Feng, Q Zhang, D Guo, L Zhang… - Emerging microbes & …, 2020 - Taylor & Francis
Different primers/probes sets have been developed all over the world for the nucleic acid
detection of SARS-CoV-2 by quantitative real time polymerase chain reaction (qRT-PCR) as …

[HTML][HTML] Comparison of digital PCR and quantitative PCR with various SARS-CoV-2 primer-probe sets

C Park, J Lee, Z Ul Hassan, KB Ku, SJ Kim… - … of Microbiology and …, 2021 - ncbi.nlm.nih.gov
Abstract The World Health Organization (WHO) has declared the coronavirus disease 2019
(COVID-19) as an international health emergency. Current diagnostic tests are based on the …

SARS-CoV-2 detection using digital PCR for COVID-19 diagnosis, treatment monitoring and criteria for discharge

R Lu, J Wang, M Li, Y Wang, J Dong, W Cai - MedRxiv, 2020 - medrxiv.org
Background SARS-CoV-2 nucleic acid detection by RT-PCR is one of the criteria approved
by China FDA for diagnosis of COVID-19. However, inaccurate test results (for example …

Digital PCR is a sensitive new technique for SARS-CoV-2 detection in clinical applications

Y Jiang, H Wang, S Hao, Y Chen, J He, Y Liu… - Clinica Chimica …, 2020 - Elsevier
The global coronavirus disease 2019 (COVID-19) pandemic has posed great challenges in
people's daily lives. Highly sensitive laboratory techniques played a critical role in clinical …