[HTML][HTML] Everolimus and erlotinib as second-or third-line therapy in patients with advanced non–small-cell lung cancer

VA Papadimitrakopoulou, JC Soria, A Jappe… - Journal of Thoracic …, 2012 - Elsevier
Introduction The epidermal growth factor receptor inhibitor erlotinib is an approved treatment
for chemotherapy-refractory advanced non–small-cell lung cancer (NSCLC). Because …

Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non–small-cell lung cancer

GJ Riely, NA Rizvi, MG Kris, DT Milton… - Journal of Clinical …, 2009 - ascopubs.org
Purpose A prior study demonstrated that addition of continuous daily erlotinib fails to
improve response rate or survival in non–small-cell lung cancer (NSCLC) patients treated …

Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer

DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
Purpose Sorafenib, an oral multikinase inhibitor, has shown preliminary activity in non–small-
cell lung cancer (NSCLC). Patients with advanced NSCLC were treated with erlotinib with or …

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised …

MC Garassino, O Martelli, M Broggini, G Farina… - The lancet …, 2013 - thelancet.com
Background Erlotinib is registered for treatment of all patients with advanced non-small-cell
lung cancer (NSCLC). However, its efficacy for treatment of patients whose tumours are …

Efficacy and safety of erlotinib in the treatment of metastatic non-small-cell lung cancer

S Ricciardi, S Tomao, F de Marinis - Lung Cancer: Targets and …, 2010 - Taylor & Francis
Lung cancer is the leading cause of cancer deaths worldwide. Targeting the epidermal
growth factor receptor (EGFR) has played a central role in advancing non-small-cell lung …

Randomized proteomic stratified phase III study of second-line erlotinib (E) versus chemotherapy (CT) in patients with inoperable non-small cell lung cancer (PROSE).

C Lazzari, S Novello, S Barni, M Aieta, F De Marinis… - 2013 - ascopubs.org
LBA8005 Background: Second-line therapy for advanced NSCLC patients (pts) after
progression on platinum-based regimens typically employs CT or E. Improved PFS in E …

[引用][C] P-611 Final results from a phase II study of erlotinib (TarcevaTM) monotherapy in patients with advanced non-small cell lung cancer following failure of platinum …

R Perez-Soler, A Chachoua, M Huberman, D Karp… - Lung Cancer, 2003 - infona.pl
P-611 Final results from a phase II study of erlotinib (TarcevaTM) monotherapy in patients with
advanced non-small cell lung cancer following failure of platinum-based chemotherapy × …

[HTML][HTML] A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC)

HJM Groen, MA Socinski, F Grossi, E Juhasz… - Annals of oncology, 2013 - Elsevier
Background Combined inhibition of vascular, platelet-derived, and epidermal growth factor
receptor (EGFR) pathways may overcome refractoriness to single agents in platinum …

[HTML][HTML] Erlotinib in advanced non-small cell lung cancer: efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study

M Reck, N van Zandwijk, C Gridelli, Z Baliko… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Erlotinib is a small molecule inhibitor of epidermal growth factor receptor
tyrosine-kinase activity that has been shown to significantly increase survival for patients …

[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study

K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
Introduction The aim of this study was to evaluate the efficacy and safety of Erlotinib in
Japanese patients with previously treated non-small cell lung cancer (NSCLC). Available …