Size-dependent gene delivery of amine-modified silica nanoparticles
Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …
insights into the effect of particle size on gene transfection efficiency, amine-modified …
The shape and size effects of polycation functionalized silica nanoparticles on gene transfection
X Lin, N Zhao, P Yan, H Hu, FJ Xu - Acta biomaterialia, 2015 - Elsevier
Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …
viral gene carriers, owing to their controlled morphologies, potential of facile surface …
Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo
MNV Kumar, M Sameti, SS Mohapatra… - … of nanoscience and …, 2004 - ingentaconnect.com
The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …
Recent advances in the rational design of silica-based nanoparticles for gene therapy
Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …
Rambutan-like silica nanoparticles at tailored particle sizes for plasmid DNA delivery
Silica nanoparticles (SNPs) have attracted widespread attention as biocompatible and
efficient nanocarriers for gene delivery. The physicochemical properties of SNPs such as …
efficient nanocarriers for gene delivery. The physicochemical properties of SNPs such as …
Biodegradable nano-organosilica gene carrier for high-efficiency gene transfection
K Zeng, L Ma, W Yang, S Lei, M Wang, Y You… - Journal of Materials …, 2020 - pubs.rsc.org
Finding and exploiting safe and high-efficiency gene carriers have always been critical tasks
for gene therapy. In this work, novel GSH-triggered degradable organosilica nanoparticles …
for gene therapy. In this work, novel GSH-triggered degradable organosilica nanoparticles …
Silica-based gene delivery systems: From design to therapeutic applications
Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …
Silica nanoparticle is a possible safe carrier for gene therapy
In order to develop a safe and effective gene therapy carrier, some toxicological and
biodynamical experiments were carried out on silica nanoparticles (SiNPs). First we …
biodynamical experiments were carried out on silica nanoparticles (SiNPs). First we …
Nonviral gene delivery: thinking of silica.
D Luo, WM Saltzman - Gene therapy, 2006 - nature.com
We have known for a while that silica is a promising candidate gene delivery vector. New in
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …
A novel gene carrier based on amino-modified silica nanoparticles
X He, K Wang, W Tan, B Liu, X Lin, S Huang, D Li… - Chinese Science …, 2003 - Springer
Uniform-sized amino-modified silica nanoparticles have been prepared by the controlled
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …