Neutrophils are constantly produced in large numbers in the bone marrow, and the same
numbers of cells need to die within a defined time period in order to keep cellular …

Human neutrophils constitutively undergo apoptosis and this process is critical for the
resolution of inflammation. Whilst neutrophil apoptosis can be modulated by a wide variety …

Neutrophils are essential for host defense and their programmed cell death and removal are
critical for the optimal expression as well as for efficient resolution of inflammation. Delayed …

Analyses of neutrophil death mechanisms have revealed many similarities with other cell
types; however, a few important molecular features make these cells unique executors of …

Neutrophil constitutive death is a critical cellular process for modulating neutrophil number
and function, and it plays an essential role in neutrophil homeostasis and the resolution of …

Polymorphonuclear leukocytes (PMNs or neutrophils) are the most prominent cellular
component of the innate immune system in humans and produce an array of potent cytotoxic …

Neutrophil apoptosis represents a crucial step in the mechanisms governing the resolution
of neutrophilic inflammation. Several soluble mediators of inflammation modulate neutrophil …

Neutrophils are the most abundant cell type involved in the innate immune response. They
are rapidly recruited to sites of injury or infection where they engulf and kill invading …

Neutrophils (also called polymorphonuclear leukocytes, PMNs) are the most abundant white
blood cells in humans and play a central role in innate host defense. Another distinguishing …

The balance between polymorphonuclear leukocytes (PMNL) apoptosis and necrosis in
inflamed tissues is an important determinant of the degree of tissue injury. To prevent …