Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms
C Varela, C Melim, BG Neves, J Sharifi-Rad… - Journal of Translational …, 2022 - Springer
Since ancient times, plants have been an extensive reservoir of bioactive compounds with
therapeutic interest for new drug development and clinical application. Cucurbitacins are a …
therapeutic interest for new drug development and clinical application. Cucurbitacins are a …
[HTML][HTML] Cucurbitacins–a promising target for cancer therapy
AA Alghasham - International journal of health sciences, 2013 - ncbi.nlm.nih.gov
During the last decades a large number of cucurbitacins have been isolated from various
plant species belonging to other plant families than Cucurbitaceae. Although the roots and …
plant species belonging to other plant families than Cucurbitaceae. Although the roots and …
Cucurbitacins as anticancer agents: a patent review
Background: Cucurbitacins belong to a group of tetracyclic triterpenoids that display a wide
range of biological effects. In the past, numerous cucurbitacins have been isolated from …
range of biological effects. In the past, numerous cucurbitacins have been isolated from …
Recent Advances in the Application of Cucurbitacins as Anticancer Agents
B Zieniuk, M Pawełkowicz - Metabolites, 2023 - mdpi.com
Cucurbitacins are tetracyclic triterpenoid secondary metabolites, widely distributed in the
Cucurbitaceae family. These bitter-tasting compounds act primarily as defense mechanisms …
Cucurbitaceae family. These bitter-tasting compounds act primarily as defense mechanisms …
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer
Cucurbitacin and its derivatives (cucurbitacins) are a class of highly oxidized tetracyclic
triterpenoids. They are widely distributed in the plant kingdom, where they act as …
triterpenoids. They are widely distributed in the plant kingdom, where they act as …
Cucurbitacins: a systematic review of the phytochemistry and anticancer activity
Cucurbitacins are highly oxidized tetracyclic triterpenoids that are widely present in
traditional Chinese medicines (Cucurbitaceae family), possess strong anticancer activity …
traditional Chinese medicines (Cucurbitaceae family), possess strong anticancer activity …
[HTML][HTML] Potential of cucurbitacin as an anticancer drug
Y Li, Y Li, Y Yao, H Li, C Gao, C Sun… - Biomedicine & …, 2023 - Elsevier
Abstract In Chinese medicine, the Cucurbitaceae family contains many compounds known
as cucurbitacins, which have been categorized into 12 classes ranging from A to T and more …
as cucurbitacins, which have been categorized into 12 classes ranging from A to T and more …
Apoptotic and antimetastatic effect of cucurbitacins in cancer: Recent trends and advancement
The Cucurbitaceae family produces a class of secondary metabolites known as
cucurbitacins. The eight cucurbitacin subunits are cucurbitacin B, D, E, I, IIa, L glucoside, Q …
cucurbitacins. The eight cucurbitacin subunits are cucurbitacin B, D, E, I, IIa, L glucoside, Q …
Cucurbitacin: ancient compound shedding new light on cancer treatment
DH Lee, GB Iwanski… - The scientific world …, 2010 - Wiley Online Library
Cucurbitacins and their derivatives are triterpenoids found in medicinal plants known for
their diverse pharmacological and biological activities, including anticancer effects …
their diverse pharmacological and biological activities, including anticancer effects …
[PDF][PDF] An updated review of cucurbitacins and their biological and pharmacological activities
Cucurbitacins (Cus) are a class of highly oxidized tetracyclic triterpenoids that confer a bitter
taste to cucurbits such as cucumber, melon, watermelon, squash, and pumpkin. To date, a …
taste to cucurbits such as cucumber, melon, watermelon, squash, and pumpkin. To date, a …