Increased immunogenicity and protective efficacy of a P. aeruginosa vaccine in mice using an alum and de-O-acylated lipooligosaccharide adjuvant system

JI Ryu, SR Wui, A Ko, HTT Do, YJ Lee… - … of microbiology and …, 2017 - koreascience.kr
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen that commonly
causes fatal infections in cystic fibrosis and burn patients as well as in patients who are …

Immunological evaluation of an alginate‐based conjugate as a vaccine candidate against Pseudomonas aeruginosa

A Farjah, P Owlia, SD Siadat, SF Mousavi… - Apmis, 2015 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen that causes serious infections, is
usually resistant to antimicrobial agents, and is the leading cause of morbidity and …

[HTML][HTML] Synthesis, characterization, and immunological properties of LPS-based vaccines composed of O-polysaccharides conjugated with recombinant exoprotein a …

NF Abu-Baker, H Masoud - Advances in Microbiology, 2016 - scirp.org
Pseudomonas aeruginosa remains one of the major pathogens affecting
immunocompromised patients. LPS-based monovalent (MV) and polyvalent (PV) conjugate …

LPS-based conjugate vaccines composed of O-polysaccharide from Pseudomonas aeruginosa IATS 6 and 11 bound to a carrier protein

M Al-Zeer, H Masoud - World Journal of Microbiology and Biotechnology, 2007 - Springer
Lipopolysaccharide (LPS) is the major surface antigen of Pseudomonas aeruginosa and
elicits protective antibodies in animals. No cross reaction was observed between LPSs of P …

Conjugation of alginate to a synthetic peptide containing T-and B-cell epitopes as an induction for protective immunity against Pseudomonas aeruginosa

A Farjah, P Owlia, SD Siadat, SF Mousavi… - Journal of …, 2014 - Elsevier
Pseudomonas aeruginosa is a major cause of respiratory tract infections worldwide,
particularly in hospitalized patients with immunosuppressed conditions and cystic fibrosis …

Mannose-modified chitosan microspheres enhance OprF-OprI-mediated protection of mice against Pseudomonas aeruginosa infection via induction of mucosal …

Z Cui, D Han, X Sun, M Zhang, X Feng, C Sun… - Applied microbiology …, 2015 - Springer
Pseudomonas aeruginosa is an opportunistic pathogen that localizes to and colonizes
mucosal tissue. Thus, vaccines that elicit a strong mucosal response against P. aeruginosa …

Monoclonal antibodies against lipopolysaccharide protect against Pseudomonas aeruginosa challenge in mice

J Kang, M Mateu-Borrás, HL Monroe… - Frontiers in Cellular …, 2023 - frontiersin.org
Pseudomonas aeruginosa is a common cause of hospital-acquired infections, including
central line-associated bloodstream infections and ventilator-associated pneumonia …

A Semisynthetic Oligomannuronic Acid-Based Glycoconjugate Vaccine against Pseudomonas aeruginosa

Y Zhang, X Wang, Y Liang, L Zhang, J Fan… - ACS Central …, 2024 - ACS Publications
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections and has
become increasingly resistant to multiple antibiotics. However, development of novel …

Design of a Liposomal Candidate Vaccine Against Pseudomonas aeruginosa and its Evaluation in Triggering Systemic and Lung Mucosal Immunity

B Heurtault, P Gentine, JS Thomann, C Baehr… - Pharmaceutical …, 2009 - Springer
Purpose To design and evaluate liposomal constructs capable of inducing a potent systemic
and airway humoral response to Pseudomonas aeruginosa Methods Liposomes contained …

Pseudomonas aeruginosa PAO1 outer membrane vesicles-diphtheria toxoid conjugate as a vaccine candidate in a murine burn model

E Zare Banadkoki, I Rasooli, T Ghazanfari… - Scientific Reports, 2022 - nature.com
Pseudomonas aeruginosa is an opportunistic pathogen considered a common cause of
nosocomial infection with high morbidity and mortality in burn patients. Immunoprophylaxis …