RIP-B7. 1 transgenic mice express B7. 1 costimulatory molecules in pancreatic islets and
develop diabetes after treatment with polyinosinic: polycytidylic acid (poly I: C), a synthetic …

The rising prevalence of type 1 diabetes (T1D) over the past decades has been linked to
lifestyle changes, but the underlying mechanisms are largely unknown. Recent findings …

Environmental factors and host genetics interact to control the gut microbiota, which may
have a role in the development of obesity and insulin resistance. TLR2-deficient mice, under …

The authors and editors retract this publication following an investigation into concerns
around the data presented in several figures that were brought to the editors' attention. The …

The incidence of type 1 diabetes (T1D) is determined by both genetic and environmental
factors. In recent years, the gut microbiota have been identified to be an important …

Accumulating evidence supports that the intestinal microbiome is involved in Type 1
diabetes (T1D) pathogenesis through the gut-pancreas nexus. Our aim was to determine …

Introduction Environmental factors have a key role in the control of gut microbiota and
obesity. TLR2 knockout (TLR2−/−) mice in some housing conditions are protected from diet …

Introduction The incidence of the autoimmune disease, type 1 diabetes (T1D), has been
increasing worldwide and recent studies have shown that the gut microbiota are associated …

Deletion of the innate immune adaptor myeloid differentiation primary response gene 88
(MyD88) in the nonobese diabetic (NOD) mouse model of type 1 diabetes (T1D) results in …

Introduction Type 1 diabetes (T1D) is an autoimmune disease characterized by the
destruction of insulin-producing β cells. Toll-like receptor 9 (TLR9) plays a role in …