Microbial Cleavage of C–F Bonds in Two C6 Per- and Polyfluorinated Compounds via Reductive Defluorination

Y Yu, K Zhang, Z Li, C Ren, J Chen… - … science & technology, 2020 - ACS Publications
The C–F bond is one of the strongest single bonds in nature. Although microbial reductive
dehalogenation is well known for the other organohalides, no microbial reductive …

Microbial defluorination of unsaturated per-and polyfluorinated carboxylic acids under anaerobic and aerobic conditions: a structure specificity study

Y Yu, S Che, C Ren, B Jin, Z Tian, J Liu… - … science & technology, 2022 - ACS Publications
The recently discovered microbial reductive defluorination of two C6 branched and
unsaturated fluorinated carboxylic acids (FCAs) provided valuable insights into the …

Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances

LP Wackett - Microbial biotechnology, 2022 - Wiley Online Library
Poly‐and perfluorinated chemicals, including perfluorinated alkyl substances (PFAS), are
pervasive in today's society, with a negative impact on human and ecosystem health …

Structure-specific aerobic defluorination of short-chain fluorinated carboxylic acids by activated sludge communities

S Che, B Jin, Z Liu, Y Yu, J Liu… - Environmental science & …, 2021 - ACS Publications
Per-and polyfluoroalkyl substances (PFAS) are a large group of manmade chemicals that
impose emerging environmental concerns. Among them, short-chain per-and …

Reductive defluorination of branched per-and polyfluoroalkyl substances with cobalt complex catalysts

J Liu, DJ Van Hoomissen, T Liu, A Maizel… - … & Technology Letters, 2018 - ACS Publications
This study investigates structure–reactivity relationships within branched per-and
polyfluoroalkyl substances (PFASs) undergoing cobalt-catalyzed reductive defluorination …

Why is the biodegradation of polyfluorinated compounds so rare?

LP Wackett - Msphere, 2021 - Am Soc Microbiol
Thousands of heavily fluorinated chemicals are found in the environment, impact human
and ecosystem health, and are relatively resistant to biological and chemical degradation …

The biodegradation vs. biotransformation of fluorosubstituted aromatics

M Kiel, KH Engesser - Applied Microbiology and Biotechnology, 2015 - Springer
Fluoroaromatics are widely and—in recent years—increasingly used as agrochemicals,
starting materials for chemical syntheses and especially pharmaceuticals. This originates …

Microbial degradation of polyfluoroalkyl chemicals in the environment: a review

J Liu, SM Avendaño - Environment international, 2013 - Elsevier
Polyfluoroalkyl chemicals containing perfluoroalkyl moieties have been widely used in
numerous industrial and commercial applications. Many polyfluoroalkyl chemicals are …

Mapping the reaction coordinates of enzymatic defluorination

PWY Chan, AF Yakunin, EA Edwards… - Journal of the American …, 2011 - ACS Publications
The carbon− fluorine bond is the strongest covalent bond in organic chemistry, yet
fluoroacetate dehalogenases can readily hydrolyze this bond under mild physiological …

Biodegradation and biotransformation of organofluorine compounds

CD Murphy - Biotechnology letters, 2010 - Springer
The carbon–fluorine bond is one of the strongest in nature, and the increasing use of
organofluorine compounds in agriculture, human and veterinary medicine, and industry has …