The sepsis syndrome, or systemic inflammatory response syndrome (SIRS) associated with
infection, is characterized by exacerbation of the production of pro-inflammatory mediators …

Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality
globally. Recent decades have seen the evolution of international collaborations to improve …

Sepsis remains a major cause of morbidity and mortality mainly because of sepsis-induced
multiple organ dysfunction. In contrast to preclinical studies, most clinical trials of promising …

There have been many attempts to provide a uniform definition for the diagnosis of sepsis
that can be used for research and clinical purposes. Several definitions are too broad and …

The history of sepsis demonstrates that despite current knowledge about its pathogenesis
the definition of sepsis is more contested than ever. However, a definite terminology is …

Sepsis results from the activation of a complex cascade of mediators, an appropriate and
necessary body response to infection or insult which can, however, become excessive and …

Introduction: The incidence of sepsis, the systemic inflammatory response of the host to an
infectious insult, has steadily increased over past decades. This trend is expected to …

This common syndrome, responsible for killing hundreds of thousands of patients each year
in the United States alone [1], was defined by a consensus statement in 1992 to consist of …

Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …

Of the World Health Organization top 10 causes of death, 4 fulfill the definition of sepsis
(www. who. int). Sepsis occurs when infection results in systemic inflammation 1, 2 and is …