[HTML][HTML] A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

W Enard, S Gehre, K Hammerschmidt, SM Hölter… - Cell, 2009 - cell.com
It has been proposed that two amino acid substitutions in the transcription factor FOXP2
have been positively selected during human evolution due to effects on aspects of speech …

Foxp2 mediates sex differences in ultrasonic vocalization by rat pups and directs order of maternal retrieval

JM Bowers, M Perez-Pouchoulen… - Journal of …, 2013 - Soc Neuroscience
The FOXP2 gene is central to acquisition of speech and language in humans and vocal
production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) …

Genetics of language disorders: Clinical conditions, phenotypes, and genes

ML Rice, F Smolík - 2007 - academic.oup.com
Persons who do not acquire language in the expected ways show variation that can be
linked or associated with genetic variations. Just as in ancient times, there is great interest in …

The FOXP2 gene, human cognition and language

P Lieberman - International Congress Series, 2006 - Elsevier
The creative “reiterative” powers of human language and thought appear to have evolved
from brain mechanisms initially adapted for motor control. Humans can form a potentially …

Human-specific transcriptional regulation of CNS development genes by FOXP2

G Konopka, JM Bomar, K Winden, G Coppola… - Nature, 2009 - nature.com
The signalling pathways controlling both the evolution and development of language in the
human brain remain unknown. So far, the transcription factor FOXP2 (forkhead box P2) is …

Accelerated protein evolution and origins of human-specific features: Foxp2 as an example

J Zhang, DM Webb, O Podlaha - Genetics, 2002 - academic.oup.com
Genes responsible for human-specific phenotypes may have been under altered selective
pressures in human evolution and thus exhibit changes in substitution rate and pattern at the …

FoxP2 regulates neurogenesis during embryonic cortical development

D Tsui, JP Vessey, H Tomita, DR Kaplan… - Journal of …, 2013 - Soc Neuroscience
The transcription factor FoxP2 has been associated with the development of human speech
but the underlying cellular function of FoxP2 is still unclear. Here we provide evidence that …

Evo-devo, deep homology and FoxP2: implications for the evolution of speech and language

C Scharff, J Petri - … Transactions of the Royal Society B …, 2011 - royalsocietypublishing.org
The evolution of novel morphological features, such as feathers, involves the modification of
developmental processes regulated by gene networks. The fact that genetic novelty …

[PDF][PDF] Human evolution: Neandertal gene speaks out

E Trinkaus - Current Biology, 2007 - cell.com
Human Evolution: Neandertal Gene Speaks out Page 1 finding that myosin VI association with
endocytic vesicles promotes dimerization, a switch likely to be essential for processive …

Conservation and diversity of Foxp2 expression in muroid rodents: functional implications

P Campbell, RL Reep, ML Stoll… - Journal of …, 2009 - Wiley Online Library
FOXP2, the first gene causally linked to a human language disorder, is implicated in song
acquisition, production, and perception in oscine songbirds, the evolution of speech and …