Language fMRI abnormalities associated with FOXP2 gene mutation

F Liégeois, T Baldeweg, A Connelly, DG Gadian… - Nature …, 2003 - nature.com
Half the members of the KE family suffer from a speech and language disorder caused by a
mutation in the FOXP2 gene. We examined functional brain abnormalities associated with …

Transcriptional Enhancers in the FOXP2 Locus Underwent Accelerated Evolution in the Human Lineage

AL Caporale, CM Gonda… - Molecular biology and …, 2019 - academic.oup.com
Unique human features, such as complex language, are the result of molecular evolutionary
changes that modified developmental programs of our brain. The human-specific evolution …

Behavior-linked FoxP2 regulation enables zebra finch vocal learning

JB Heston, SA White - Journal of Neuroscience, 2015 - Soc Neuroscience
Mutations in the FOXP2 transcription factor cause an inherited speech and language
disorder, but how FoxP2 contributes to learning of these vocal communication signals …

Neuroanatomy of the grey seal brain: bringing pinnipeds into the neurobiological study of vocal learning

N Hoeksema, L Verga, J Mengede… - … of the Royal …, 2021 - royalsocietypublishing.org
Comparative animal studies of complex behavioural traits, and their neurobiological
underpinnings, can increase our understanding of their evolution, including in humans …

FOXP2 and the mirror system

MC Corballis - Trends in cognitive sciences, 2004 - cell.com
An inherited deficit in spoken language has been associated with a mutation in the forkhead
box P2 (FOXP2) gene on chromosome 7. A recent functional magnetic resonance imaging …

Twitter evolution: converging mechanisms in birdsong and human speech

JJ Bolhuis, K Okanoya, C Scharff - Nature Reviews Neuroscience, 2010 - nature.com
Vocal imitation in human infants and in some orders of birds relies on auditory-guided motor
learning during a sensitive period of development. It proceeds from'babbling'(in humans) …

Differential song deficits after lentivirus-mediated knockdown of FoxP1, FoxP2, or FoxP4 in area X of juvenile zebra finches

P Norton, P Barschke, C Scharff… - Journal of …, 2019 - Soc Neuroscience
Mutations in the transcription factors FOXP1 and FOXP2 are associated with speech
impairments. FOXP1 is additionally linked to cognitive deficits, as is FOXP4. These FoxP …

Evidence against a genetic-based revolution in language 50,000 years ago

KC Diller, RL Cann - The cradle of language, 2009 - books.google.com
Africa was more than just the ''cradle''of language, a place of nurture for language and for the
anatomically modern humans who have had full capacity for language for more than …

Altered social behavior in mice carrying a cortical Foxp2 deletion

VP Medvedeva, MA Rieger, B Vieth… - Human molecular …, 2019 - academic.oup.com
Genetic disruptions of the forkhead box transcription factor FOXP2 in humans cause an
autosomal-dominant speech and language disorder. While FOXP2 expression pattern are …

Human brain evolution: from gene discovery to phenotype discovery

TM Preuss - Proceedings of the National Academy of …, 2012 - National Acad Sciences
The rise of comparative genomics and related technologies has added important new
dimensions to the study of human evolution. Our knowledge of the genes that underwent …