Diets replete with n− 3 PUFAs (polyunsaturated fatty acids) are known to have therapeutic
potential for the heart, although a specifically defined duration of the n− 3 PUFA diet …

Increased awareness of obesity has led to a dietary shift toward “heart-friendly” vegetable
oils containing ω-6 polyunsaturated fatty acid (ω-6 PUFA). In addition to its beneficial effects …

Reactive oxygen species paradoxically underpin both ischaemia/reperfusion (I/R) damage
and ischaemic preconditioning (IPC) cardioprotection. Long-chain omega-3 polyunsaturated …

Studies in experimental models suggest that n-3 polyunsaturated fatty acids (PUFAs)
improve metabolic and anti-inflammatory/antioxidant capacity of the heart, although the …

Transcription factor Nrf2 (NF-E2 p45-related factor 2) regulates the cellular redox
homoeostasis and cytoprotective responses, allowing adaptation and survival under …

Rationale and Methods: Skeletal muscle derangements, potentially including mitochondrial
dysfunction with altered mitochondrial dynamics and high reactive oxygen species (ROS) …

Polyunsaturated fatty acids (PUFA) are fundamental building materials for cells and play
crucial function as signaling molecules. When PUFA are used as substrates for non …

Currently, controversial clinical data about the protective effects in the consumption of n‐3
polyunsaturated fatty acids (PUFAs) in ischaemic heart diseases exist. Improved myocardial …

Polyunsaturated fatty acid (PUFA) peroxidation is initiated by hydrogen atom abstraction at
bis-allylic sites and sets in motion a chain reaction that generates multiple toxic products …

Age-related changes in cardiomyocytes reduce the capacity to recover from acute injury or
to adapt during chronic disease in advanced age. N-6 polyunsaturated fatty acids (n-6PUFA) …