Intensive, myelosuppressive therapy is necessary to maximize outcomes for patients with
acute myeloid leukemia (AML). A comparison was made of 3 aggressive postremission …

Background The value of autologous bone marrow transplantation in the treatment of
children with acute myeloid leukemia (AML) is unknown. We compared autologous bone …

PURPOSE This study was conducted to assess the comparative values of allogeneic bone
marrow transplantation (BMT) and autologous bone marrow transplantation (ABMT) with …

PURPOSE In an effort to evaluate the usefulness of bone marrow transplantation, the
Childrens Cancer Group (CCG) initiated a multiinstitutional study comparing bone marrow …

PURPOSE The objectives of this study were to determine if the addition of etoposide,
thioguanine, and dexamethasone to daunorubicin and cytarabine (five-drug regimen) during …

PURPOSE Childrens Cancer Group (CCG) protocol 2861 was designed to test the feasibility
of aggressively timed induction therapy followed by autologous or allogeneic bone marrow …

359 eligible children with acute myeloid leukaemia (AML) entered the MRC AML 10 trial
between May 1988 and March 1995. Patients received four courses of intensive induction …

Abstract The Children's Cancer Group (CCG) conducted three Phase III prospective clinical
trials for children with de novo acute myeloid leukemia between the years 1979 and 1995. A …

From 1981 to 2000, a total of 1823 children with acute myeloid leukemia (AML) enrolled on
four consecutive Pediatric Oncology Group (POG) clinical trials. POG 8101 demonstrated …

The safety and efficacy of reduced-intensity conditioning (RIC) regimens for the treatment of
pediatric acute myeloid leukemia is unknown. We compared the outcome of allogeneic …