Pulmonary arterial hypertension (PAH) is a fatal disease characterized by impaired
regulation of pulmonary hemodynamics and excessive growth and dysfunction of the …

Pulmonary hypertension (PH) is a deadly and increasingly prevalent vascular disease
characterized by excessive pulmonary vascular remodeling and right ventricular dysfunction …

Pulmonary arterial hypertension (PAH) is a vascular remodeling disease of the lungs
resulting in heart failure and premature death. Although, until recently, it was thought that …

Pulmonary arterial hypertension (PAH) is a devastating disease that is precipitated by
hypertrophic pulmonary vascular remodeling of distal arterioles to increase pulmonary artery …

Pulmonary arterial hypertension (PAH) is a devastating disease that involves pulmonary
vasoconstriction, small vessel obliteration, large vessel thickening and obstruction, and …

Mitochondria are highly dynamic organelles essential for cell metabolism, growth, and
function. It is becoming increasingly clear that endothelial cell dysfunction significantly …

Pulmonary arterial hypertension (PAH) encompasses a group of clinical entities
characterized by sustained vasoconstriction and progressive vascular remodeling that act in …

Pulmonary vascular disease can be defined as either a disease affecting the pulmonary
capillaries and pulmonary arterioles, termed pulmonary arterial hypertension, or a disease …

Idiopathic pulmonary arterial hypertension (IPAH) is characterized by plexiform vascular
lesions, which are hypothesized to arise from deregulated growth of pulmonary artery …

Severe forms of pulmonary arterial hypertension (PAH) are most frequently the
consequence of a lumen-obliterating angiopathy. One pathobiological model is that the …