Cystic fibrosis (CF) was distinguished from celiac disease in 1938. Then, it was a pathologic
diagnosis, life expectancy was approximately 6 months, and the autosomal recessive …

James M. Wilson, Editor ductance, and by analogy with the sweat duct (11, 12) this allows
salt levels in the ASL to remain at levels similar to those in plasma. The high salt in the ASL …

Cystic fibrosis is a frequent autosomal recessive disorder that is caused by the
malfunctioning of a small chloride channel, the cystic fibrosis transmembrane conductance …

Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis
transmembrane conductance regulator (CFTR), an anion channel expressed in epithelial …

Etiological therapies aim at repairing the underlying cause of cystic fibrosis (CF), which is
the functional defect of the cystic fibrosis transmembrane conductance regulator (CFTR) …

Lessons from the sweat gland on cystic fibrosis (CF) began long before modern medicine
became a science. In European folklore, the curse that “a child that taste salty when kissed …

It has been nearly 10 years since the identification and cloning of the cystic fibrosis (CF)
gene was announced (1). Despite rapid advances in our understanding of the molecular …

Cystic fibrosis (CF), a monogenic disease caused by mutations in the CFTR gene on
chromosome 7, is complex and greatly variable in clinical expression. Airways, pancreas …

Cystic fibrosis (CF) is a disease caused by mutations in the cystic fibrosis transmembrane
conductance regulator (CFTR). Initially, Cl-conductance in the sweat duct was discovered to …

The cystic fibrosis (CF) drug development pipeline promises many exciting new treatments
for patients with CF, all which will require clinical studies to prove their benefits on CF lung …