Thyroid hormone influences conditional transcript elongation of the apolipoprotein AI gene in rat liver
YC Lin-Lee, SM Soyal, A Surguchov, S Sanders… - Journal of lipid …, 1995 - ASBMB
Chronic administration of thyroid hormone (T3) increases apoA-I gene expression in rat liver
by enhancing mRNA maturation, but reduces apoA-I mRNA synthesis to 50% of control. To …
by enhancing mRNA maturation, but reduces apoA-I mRNA synthesis to 50% of control. To …
Transcriptional and posttranscriptional regulation of apolipoprotein E, AI, and A-II gene expression in normal rat liver and during several pathophysiologic states
Revised Manuscript Received May 22, 1990 abstract: Assessment of the relative
transcription rates and mRNA steady-state levels for apolipoprotein genes E, AI, and A-II has …
transcription rates and mRNA steady-state levels for apolipoprotein genes E, AI, and A-II has …
The A/G polymorphism in the− 78 position of the apolipoprotein AI promoter does not have a direct effect on transcriptional efficiency
GM Danek, M Valenti, FE Baralle, M Romano - Biochimica et Biophysica …, 1998 - Elsevier
A promoter polymorphism A/G at position 78 bp upstream of the transcription initiation site
characterizes the human apolipoprotein AI gene. Some studies correlated the higher Apo AI …
characterizes the human apolipoprotein AI gene. Some studies correlated the higher Apo AI …
Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells
RL Widom, JAA Ladias, S Kouidou… - Molecular and cellular …, 1991 - Taylor & Francis
The gene coding for apolipoprotein AI (apoAI), a plasma protein involved in the transport of
cholesterol and other lipids in the plasma, is expressed predominantly in liver and intestine …
cholesterol and other lipids in the plasma, is expressed predominantly in liver and intestine …
5'control regions of the apolipoprotein (a) gene and members of the related plasminogen gene family.
DP Wade, JG Clarke, GE Lindahl… - Proceedings of the …, 1993 - National Acad Sciences
Elevated blood levels of apolipoprotein (a), the component of lipoprotein (a) that
distinguishes it from low density lipoprotein, are a major risk factor for atherosclerosis. The …
distinguishes it from low density lipoprotein, are a major risk factor for atherosclerosis. The …
Genetic variation in mouse apolipoprotein A-IV expression is determined pre-and post-transcriptionally
K Reue, DA Purcell-Huynh, TH Leete, MH Doolittle… - Journal of lipid …, 1993 - ASBMB
Among inbred mouse strains there is a striking genetic variation in the levels of
apolipoprotein A-IV (apoA-IV) mRNA in the liver, although intestinal mRNA levels vary only …
apolipoprotein A-IV (apoA-IV) mRNA in the liver, although intestinal mRNA levels vary only …
Methods of screening for compounds with ability to alter apolipoprotein AI gene expression
SK Karathanasis, JAA Ladias, JN Rottman… - US Patent …, 1998 - Google Patents
Activation of the apolipoprotein AI (apoAI) gene in mam malian liver cells has been studied,
as described herein, and shown to depend on synergistic interactions between nuclear …
as described herein, and shown to depend on synergistic interactions between nuclear …
cis-acting determinants of basal and lipid-regulated apolipoprotein A-IV expression in mice
SC Williams, SG Grant, K Reue, B Carrasquillo… - Journal of biological …, 1989 - Elsevier
The levels of apolipoprotein A-IV (apoA-IV) mRNA are regulated by dietary lipid in the liver
of both the mouse and rat. Thirteen different inbred mouse strains were fed a high lipid diet …
of both the mouse and rat. Thirteen different inbred mouse strains were fed a high lipid diet …
Purification and characterization of nuclear factors binding to the negative regulatory element D of human apolipoprotein A-II promoter: a negative regulatory effect is …
P Cardot, D Pastier, JM Lacorte, M Mangeney… - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received July 19, 1994® abstract: We have previously shown that
transcription of the human apolipoprotein A-II (apoA-II) gene is controlled by a complex set …
transcription of the human apolipoprotein A-II (apoA-II) gene is controlled by a complex set …
Plasma lipoprotein (a) levels and expression of the apolipoprotein (a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.
K Suzuki, M Kuriyama, T Saito… - The Journal of clinical …, 1997 - Am Soc Clin Investig
The apolipoprotein (a)(apo [a]) gene encodes a protein component of lipoprotein (a)[Lp (a)]
whose plasma levels vary widely among individuals. Hyper-Lp (a)-emia constitutes a risk …
whose plasma levels vary widely among individuals. Hyper-Lp (a)-emia constitutes a risk …