Transmission of HIV-1 results in the establishment of a new infection, typically starting from a
single virus particle. That virion replicates to generate viremia and persistent infection in all …

In the absence of treatment, HIV-1 infection, usually starting with a single virion, leads
inexorably to a catastrophic decline in the numbers of CD4+ T cells and to AIDS …

SUMMARY HIV‐1 and HIV‐2 share many similarities including their basic gene
arrangement, modes of transmission, intracellular replication pathways and clinical …

Over the past three decades of intense research on the contribution of viral and host factors
determining the variability in HIV-1 infection outcome, HIV pathogenesis is still a fascinating …

HIV pathogenesis: the first cut is the deepest | Nature Immunology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

In the four decades that human immunodeficiency virus type 1 (HIV-1) has afflicted the
human population, the virus has spread rapidly into most parts of the world, leading to the …

Publisher Summary This chapter reviews the state of knowledge concerning the structure
and function of the HIV genome, virus cell tropism, cytotoxic and noncytotoxic effects of HIV …

The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Great progress has been made with respect to our understanding of the
immunopathogenesis of AIDS and the infectious agent, HIV, that causes the disease. HIV, a …

The ultimate consequence of infection with HIV is profound immunosuppression that is the
result of both quantitative and qualitative abnormalities of the helper/inducer subset of T …