Aspergillus fumigatus is a mold that causes severe pulmonary infections in humans, such as
invasive pulmonary Aspergillosis (IPA). Currently, our knowledge of how A. fumigatus …

Aspergillus fumigatus airway infections are associated with increased rates of
hospitalizations and declining lung function in patients with chronic lung disease. While the …

Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of
how A. fumigatus growth is controlled in the respiratory tract is developing, but still limited …

Macrophages and neutrophils are essential components of the innate immune response of
the host to infection by microorganisms. Macrophages have three main functions:(i) to take …

Cytokine networking in the lung in response to inhaled Aspergillus fumigatus was assessed
using a murine model of primary pulmonary aspergillosis in immunocompetent Crl: CF-1 …

Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Cytokines are critical molecules necessary for normal lung pathogen host defences. Gamma
interferon (IFN-γ) and T1-phenotype immune responses are important components of host …

The human lung is continually exposed to airborne conidia of the fungus Aspergillus
fumigatus (AF) and related species. The innate immune system efficiently eliminates inhaled …

Previous studies have established that phagocytes are key cells of the pulmonary innate
immune defense against A. fumigatus, an opportunistic fungus responsible of invasive …

Alveolar macrophages and neutrophils mediate innate immune defense against the
opportunistic fungal pathogen Aspergillus fumigatus and are believed to be essential for …