Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points following Aspergillus fumigatus Infection
MM Mircescu, L Lipuma, N Van Rooijen… - The Journal of …, 2009 - academic.oup.com
Alveolar macrophages and neutrophils mediate innate immune defense against the
opportunistic fungal pathogen Aspergillus fumigatus and are believed to be essential for …
opportunistic fungal pathogen Aspergillus fumigatus and are believed to be essential for …
Innate lung defense during invasive aspergillosis: new mechanisms
JM Garth, C Steele - Journal of innate immunity, 2017 - karger.com
Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …
most lethal fungal infections known to man. Continued use of immunosuppressive agents …
Aberrant tissue localization of fungus-specific CD4+ T cells in IL-10-deficient mice
A Rivera, N Collins, MT Stephan, L Lipuma… - The Journal of …, 2009 - journals.aai.org
Aspergillus fumigatus, a common environmental fungus, can cause lethal invasive infections
in immunocompromised hosts. In immunocompetent individuals, however, inhaled A …
in immunocompromised hosts. In immunocompetent individuals, however, inhaled A …
When Aspergillus fumigatus Meets the Man
SSW Wong, JP Latgé - Current Progress in Medical Mycology, 2017 - Springer
Aspergillus fumigatus is one of the most ubiquitous opportunistic fungal pathogen, which
can cause life-threatening invasive pulmonary infections in immunocompromised …
can cause life-threatening invasive pulmonary infections in immunocompromised …
The innate immune response to Aspergillus fumigatus at the alveolar surface
A Margalit, K Kavanagh - FEMS microbiology reviews, 2015 - academic.oup.com
Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …
conidia which are inhaled by humans on a daily basis. When the immune system is …
Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia
BJ Murdock, AB Shreiner, RA McDonald… - Infection and …, 2011 - Am Soc Microbiol
Aspergillus fumigatus, a ubiquitous airborne fungus, can cause invasive infection in
immunocompromised individuals but also triggers allergic bronchopulmonary aspergillosis …
immunocompromised individuals but also triggers allergic bronchopulmonary aspergillosis …
[HTML][HTML] The innate immune response to Aspergillus fumigatus
V Balloy, M Chignard - Microbes and infection, 2009 - Elsevier
Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …
[HTML][HTML] Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-Causing Aspergillus fumigatus
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …
[HTML][HTML] Role of Germination in Murine Airway CD8+ T-Cell Responses to Aspergillus Conidia
SP Templeton, AD Buskirk, B Law, BJ Green… - PloS one, 2011 - journals.plos.org
Pulmonary exposure to Aspergillus fumigatus has been associated with morbidity and
mortality, particularly in immunocompromised individuals. A. fumigatus conidia produce β …
mortality, particularly in immunocompromised individuals. A. fumigatus conidia produce β …
[HTML][HTML] Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens
Humans are continuously exposed to airborne spores of the saprophytic fungus Aspergillus
fumigatus. However, in healthy individuals pulmonary host defense mechanisms efficiently …
fumigatus. However, in healthy individuals pulmonary host defense mechanisms efficiently …