Aspergillus species cause a range of respiratory diseases in humans. While
immunocompromised patients are at risk for the development of invasive infection with these …

Aspergillus fumigatus is the most prevalent airborne fungal pathogen responsible for fatal
invasive aspergillosis in immunocompromised patients. Upon arrival in the lung alveolus …

Aspergillus fumigatus is an important human respiratory mould pathogen. In addition to a
barrier function, airway epithelium elicits a robust defence against inhaled A. fumigatus by …

The immunocompromised airways are susceptible to infections caused by a range of
pathogens which increases the opportunity for polymicrobial interactions to occur …

Previous research indicated that hyphae of Aspergillus fumigatus (A. fumigatus) rather than
conidia could successfully build a pulmonary aspergillosis model in immunocompetent …

Abstract The interleukin (IL)-1 family consists of 11 members, which all play significant roles
in regulating inflammatory responses in the host. IL-1α and IL-1β exert potent pro …

We have used interleukin-10 (IL-10) gene knockout mice (IL-10−/−) to examine the role of
endogenous IL-10 in allergic lung responses to Aspergillus fumigatus Ag. In vitro …

Invasive pulmonary aspergillosis induced by the pathogenic fungus Aspergillus fumigatus is
one of the common fatal complications in immunocompromised patients. Lung epithelial …

Aspergillus fumigatus, a ubiquitous fungus, causes invasive disease in
immunocompromised humans. Although monocytes and antigen-specific CD4 T cells …

Background: Exposure to Aspergillus fumigatus allergens results in enhanced total serum
IgE and peripheral blood eosinophils in mice. The associated pulmonary inflammation and …