Immunoproteomic Analysis of Proteins Expressed by Two Related Pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during Human Infection

M Shinoy, R Dennehy, L Coleman, S Carberry… - PLoS …, 2013 - journals.plos.org
Burkholderia cepacia complex (Bcc) is an opportunistic bacterial pathogen that causes
chronic infections in people with cystic fibrosis (CF). It is a highly antibiotic resistant …

The Burkholderia cenocepacia OmpA-like protein BCAL2958: identification, characterization, and detection of anti-BCAL2958 antibodies in serum from B. cepacia …

SA Sousa, M Morad, JR Feliciano, T Pita, S Nady… - AMB Express, 2016 - Springer
Respiratory infections by bacteria of the Burkholderia cepacia complex (Bcc) remain an
important cause of morbidity and mortality among cystic fibrosis patients, highlighting the …

Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome

SA Sousa, AMM Seixas, M Mandal… - Vaccines, 2020 - mdpi.com
Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to
cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect …

Proteomic Profiling of Burkholderia cenocepacia Clonal Isolates with Different Virulence Potential Retrieved from a Cystic Fibrosis Patient during Chronic Lung …

A Madeira, SC dos Santos, PM Santos, CP Coutinho… - PLoS …, 2013 - journals.plos.org
Respiratory infections with Burkholderia cepacia complex (Bcc) bacteria in cystic fibrosis
(CF) are associated with a worse prognosis and increased risk of death. In this work, we …

Burkholderia cepacia Complex: Emerging Multihost Pathogens Equipped with a Wide Range of Virulence Factors and Determinants

SA Sousa, CG Ramos, JH Leitao - International journal of …, 2011 - Wiley Online Library
The Burkholderia cepacia complex (Bcc) comprises at least 17 closely‐related species of
the β‐proteobacteria subdivision, widely distributed in natural and man‐made inhabitats …

Postgenomic Approaches and Bioinformatics Tools to Advance the Development of Vaccines against Bacteria of the Burkholderia cepacia Complex

SA Sousa, AMM Seixas, JH Leitão - Vaccines, 2018 - mdpi.com
Bacteria of the Burkholderia cepacia complex (Bcc) remain an important cause of morbidity
and mortality among patients suffering from cystic fibrosis. Eradication of these pathogens by …

[HTML][HTML] Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence

P Drevinek, E Mahenthiralingam - Clinical Microbiology and Infection, 2010 - Elsevier
Burkholderia cepacia complex (Bcc) bacteria have gained notoriety as pathogens in cystic
fibrosis (CF) because they are difficult to identify and treat, and also have the ability to …

The Role of Mucoidy in Virulence of Bacteria from the Burkholderia cepacia Complex: A Systematic Proteomic and Transcriptomic Analysis

JEA Zlosnik, DP Speert - The Journal of infectious diseases, 2010 - academic.oup.com
Bacteria of the Burkholderia cepacia complex (BCC) are associated with severe infection in
cystic fibrosis. Recent evidence shows that the mucoid phenotype is common in BCC …

Assessment of Fluorescent In Situ Hybridization and PCR-Based Methods for Rapid Identification of Burkholderia cepacia Complex Organisms Directly from Sputum …

AR Brown, JRW Govan - Journal of clinical microbiology, 2007 - Am Soc Microbiol
Several species within the Burkholderia cepacia complex (BCC) have emerged as
significant opportunistic pathogens of patients with cystic fibrosis (CF). BCC infection is …

Accurate identification and epidemiological characterization of Burkholderia cepacia complex: an update

NK Devanga Ragupathi, B Veeraraghavan - Annals of clinical …, 2019 - Springer
Bacteria belonging to the Burkholderia cepacia complex (Bcc) are among the most important
pathogens isolated from cystic fibrosis (CF) patients and in hospital acquired infections …