Impact of tumor genomic mutations on thrombotic risk in cancer patients

O Leiva, JM Connors, H Al-Samkari - Cancers, 2020 - mdpi.com
Venous thromboembolism (VTE) is common in patients with cancer and is an important
contributor to morbidity and mortality in these patients. Early thromboprophylaxis initiated …

[HTML][HTML] Cancer‐associated thrombosis: The search for the holy grail continues

B Ünlü, HH Versteeg - Research and Practice in Thrombosis and …, 2018 - Elsevier
Cancer patients have an increased risk of developing venous thromboembolism (VTE), a
condition that is associated with increased morbidity and mortality. Although risk assessment …

Inherited thrombophilia gene mutations and risk of venous thromboembolism in patients with cancer: A systematic review and meta‐analysis

DC Roy, TF Wang, R Lun, A Zahrai… - American Journal of …, 2024 - Wiley Online Library
In the general population, individuals with an inherited thrombophilia have a higher risk of
thrombosis, but the effect of inherited thrombophilia on the risk of cancer‐associated venous …

A clinical-genetic risk score for predicting cancer-associated venous thromboembolism: a development and validation study involving two independent prospective …

A Muñoz, C Ay, E Grilz, S López, C Font… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Venous thromboembolism (VTE) is a leading cause of death among patients with
cancer. The Khorana score was developed for assessing the risk of VTE in outpatients with …

Tumor genomic profile is associated with arterial thromboembolism risk in patients with solid cancer

S Feldman, D Gupta, BB Navi, KW Grace Ho, P Willeit… - Cardio Oncology, 2023 - jacc.org
Background Patients with cancer have an increased risk for arterial thromboembolism (ATE).
Scant data exist about the impact of cancer-specific genomic alterations on the risk for ATE …

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

A Dunbar, KL Bolton, SM Devlin… - Blood, The Journal …, 2021 - ashpublications.org
Venous thromboembolism (VTE) associated with cancer (CAT) is a well-described
complication of cancer and a leading cause of death in patients with cancer. The purpose of …

Association between genetic mutations and risk of venous thromboembolism in patients with solid tumor malignancies: A systematic review and meta-analysis

M Abufarhaneh, RK Pandya, A Alkhaja… - Thrombosis …, 2022 - Elsevier
Background Venous thromboembolism (VTE) is a frequent complication in cancer patients
and is associated with significant morbidity, mortality, and burden on the health care system …

Thrombophilia gene mutations predict venous thromboembolism in ambulatory cancer patients receiving chemotherapy

DC Roy, TF Wang, M Carrier, R Mallick… - Journal of Thrombosis …, 2023 - Elsevier
Background Inherited thrombophilia and cancer both independently increase the risk of
venous thromboembolism (VTE). However, whether the increased VTE risk associated with …

Prothrombotic genotypes and risk of venous thromboembolism in cancer

OV Gran, SK Brækkan, JB Hansen - Thrombosis research, 2018 - Elsevier
Venous thromboembolism (VTE) is a common and potentially life-threatening complication
in cancer. Patients with cancer are at a higher risk of VTE-related complications such as …

Cancer and venous thromboembolic disease: from molecular mechanisms to clinical management

E Donnellan, B Kevane, BR Bird, F Ni Ainle - Current Oncology, 2014 - mdpi.com
Venous thromboembolism (VTE) represents a major challenge in the management of
patients with cancer. The malignant phenotype is associated with derangements in the …