Promising whole‐cell vaccines against cryptococcosis
K Ueno, S Tsuge, K Shimizu… - Microbiology and …, 2023 - Wiley Online Library
Cryptococcosis is a mycosis caused by Cryptococcus neoformans and C. gattii species
complexes. Although this infection is potentially lethal, no prophylactic vaccine is yet …
complexes. Although this infection is potentially lethal, no prophylactic vaccine is yet …
Vaccine and immunotherapeutic approaches for the prevention of cryptococcosis: lessons learned from animal models
CR Hole, FL Wormley Jr - Frontiers in microbiology, 2012 - frontiersin.org
Cryptococcus neoformans and C. gattii, the predominant etiological agents of
cryptococcosis, can cause life-threatening infections of the central nervous system in …
cryptococcosis, can cause life-threatening infections of the central nervous system in …
[HTML][HTML] Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines
R Wang, LVN Oliveira, MM Hester, D Carlson… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The fungal infection, cryptococcosis, is responsible for> 100,000 deaths annually. No
licensed vaccines are available. We explored the efficacy and immune responses of subunit …
licensed vaccines are available. We explored the efficacy and immune responses of subunit …
A call to arms: quest for a cryptococcal vaccine
MCC Van Dyke, FL Wormley - Trends in microbiology, 2018 - cell.com
Cryptococcosis remains a significant cause of morbidity and mortality world-wide,
particularly among AIDS patients. Yet, to date, there are no licensed vaccines clinically …
particularly among AIDS patients. Yet, to date, there are no licensed vaccines clinically …
[PDF][PDF] Vaccination with recombinant Cryptococcus proteins in glucan particles protects mice against cryptococcosis in a manner dependent upon mouse strain and …
CA Specht, CK Lee, H Huang, MM Hester, J Liu… - 2017 - core.ac.uk
Development of a vaccine to protect against cryptococcosis is a priority given the enormous
global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery …
global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery …
Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and …
CA Specht, CK Lee, H Huang, MM Hester, J Liu… - MBio, 2017 - Am Soc Microbiol
Development of a vaccine to protect against cryptococcosis is a priority given the enormous
global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery …
global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery …
Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens
MM Hester, CK Lee, A Abraham, P Khoshkenar… - Vaccine, 2020 - Elsevier
Meningitis due to Cryptococcus neoformans is responsible for upwards of 180,000 deaths
worldwide annually, mostly in immunocompromised individuals. Currently there are no …
worldwide annually, mostly in immunocompromised individuals. Currently there are no …
Prospects of vaccines for medically important fungi Feasibility and prospects for a vaccine to prevent cryptococcosis
A Casadevall, L Pirofski - Medical mycology, 2005 - academic.oup.com
Cryptococcosis is a relatively common fungal disease caused by Cryptococcus neoformans
that has high morbidity and mortality. Numerous studies have established the feasibility of …
that has high morbidity and mortality. Numerous studies have established the feasibility of …
Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes
Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …
Methodology for anti-cryptococcal vaccine development
AK Chaturvedi, FL Wormley - … for Invasive Fungal Infections: Methods and …, 2017 - Springer
Cryptococcus neoformans and Cryptococcus gattii, the predominant etiological agents of
cryptococcosis, are fungal pathogens that cause disease ranging from a mild pneumonia to …
cryptococcosis, are fungal pathogens that cause disease ranging from a mild pneumonia to …