Objective Synovial inflammation, a feature of both osteoarthritis (OA) and meniscal injury, is
hypothesized to be triggered in part via stimulation of Toll‐like receptors (TLRs). We …

Objective This study aims to explore the effect of paeoniflorin-6′-O-benzene sulfonate (CP-
25) on the migration of fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA) and the …

T cell immunoglobulin and mucin domain 3 (Tim-3) is a critical regulatory molecule found on
activated Th1 cells, exhausted CD8+ T cells, and resting monocytes/macrophages. Galectin …

Background Osteoarthritis (OA) is a highly degenerative joint disease, mainly companying
with progressive destruction of articular cartilage. Adipose-derived stromal cells (ADSCs) …

Rheumatoid arthritis (RA) is a highly relevant public health problem. RA fibroblast-like
synoviocytes (RAFLSs) play an important role in RA progression. Long non-coding RNA …

Interferon stimulated gene 20-kDa (ISG20) has been implicated in the pathology of
osteoarthritis (OA) and it has been separately found to be responsive to estrogen …

Rheumatoid arthritis (RA) is a systemic autoimmune disease caused by both genetic and
environmental factors. Recently, investigators have focused on the gut microbiota, which is …

Degeneration and destruction of articular cartilage are the key characteristics of
osteoarthritis (OA). In recent studies, the use of astilbin (AST), the primary active ingredient …

Objectives: Oncostatin M (OSM), a pleiotropic cytokine and a member of the gp130/IL-6
cytokine family, has been implicated in the pathogenesis of autoimmune diseases. Here we …

Abstract Galectin-3 (Gal-3), a glycan-binding protein responsible for inflammation, has been
reportedly implicated in inflammatory arthritis. This study aimed to determine clinical and …