Myopia has become a global public health concern with its increasing prevalence. It is the
interaction result of genetic and environmental factors. Exploration of the changes of …

Background Myopia is one of the major eye disorders and the global burden is increasing
rapidly. Our purpose is to systematically summarize potential metabolic biomarkers and …

Myopia is the most common form of refractive eye disease, and the prevalence is increasing
rapidly worldwide. However, the key metabolic alterations in individuals with high myopia …

Metabolomics analyzes the entire range of small molecule metabolites in biological systems
to reveal the response signals that are transmitted from “genetics and environment”, which …

Due to myopia's high incidence rate, there is a growing need for identification of myopia
mechanisms and intervention targets. Metabolomics has increasingly been used to …

Background Myopia is a prevalent eye disorder, especially among children and adolescents
in eastern Asian countries. Multiple measures have already been taken to prevent and treat …

Purpose High myopia is associated with blinding ocular morbidities. Identifying novel
biomarkers may provide clues on pathogenic pathways that are currently unknown. We …

Myopia is a globally emerging issue, with multiple medical and socio-economic burdens and
no well-established causal treatment thus far. A better insight into altered biochemical …

To investigate the metabolic difference among tissue layers of the rabbits' eye during the
development of myopia using metabolomic techniques and explore any metabolic links or …

High myopia is the common eye disorder worldwide, which may contribute to increase the
risk of serious disorders including glaucoma and cataract. Although various studies …