Histologic classification of penile intraepithelial neoplasia

EF Velazquez, A Chaux, AL Cubilla - Seminars in diagnostic pathology, 2012 - Elsevier
Penile squamous cell carcinomas (SCCs) and their corresponding precancerous lesions
can be classified in 2 major groups: human papillomavirus (HPV) related and HPV …

Distribution and characterization of subtypes of penile intraepithelial neoplasia and their association with invasive carcinomas: a pathological study of 139 lesions in …

A Chaux, EF Velazquez, A Amin, A Soskin, R Pfannl… - Human pathology, 2012 - Elsevier
We are presenting the morphological features of 121 cases of atypical penile intraepithelial
lesions. The term penile intraepithelial neoplasia (PeIN) was used to encompass all of them …

Advances in the pathology of penile carcinomas

A Chaux, AL Cubilla - Human pathology, 2012 - Elsevier
The incidence of penile cancer varies from country to country, with the highest figures
reported for countries in Africa, South America, and Asia and lowest in the United States and …

Distinctive immunohistochemical profile of penile intraepithelial lesions: a study of 74 cases

A Chaux, R Pfannl, IM Rodríguez… - The American journal …, 2011 - journals.lww.com
Several classification schemes for penile precancerous lesions have been proposed, but
none of them seems to correlate with the current understanding of penile cancer …

The spectrum of HPV-independent penile intraepithelial neoplasia: a proposal for subclassification

S Regauer, M Ermakov, K Kashofer - The American Journal of …, 2023 - journals.lww.com
Compared with vulva, precursor lesions of human papillomavirus (HPV)-independent
invasive squamous cell carcinoma (SCC) of the penis are insufficiently characterized. We …

Pathology of invasive and intraepithelial penile neoplasia

S Canete-Portillo, DF Sanchez, AL Cubilla - European Urology Focus, 2019 - Elsevier
Since 1995 it has been known that tumors harboring human papillomavirus (HPV)
preferentially show basaloid or condylomatous histological features, while HPV-negative …

[HTML][HTML] Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series

MMS Hogan, AJ Spieker, M Orejudos, T Gheit, M Herfs… - Modern Pathology, 2022 - Elsevier
Penile intraepithelial neoplasia (PeIN) is classified as human papillomavirus (HPV)-and non-
HPV-related. This classification is associated with distinct morphologic subtypes. The natural …

Epithelial lesions associated with invasive penile squamous cell carcinoma: a pathologic study of 288 cases

AL Cubilla, EF Velazquez… - International journal of …, 2004 - journals.sagepub.com
A heterogeneous spectrum of epithelial alterations and atypical lesions affect the squamous
epithelium of penile mucosal anatomical compartments. Analogous to other genital sites, the …

Histologic and immunohistochemical assessment of penile carcinomas in a North American population

MJ Mentrikoski, EB Stelow, S Culp… - The American Journal …, 2014 - journals.lww.com
Penile squamous cell carcinoma (SCC) is sometimes an aggressive disease that has a
variable worldwide incidence, in part due to differing rates of inflammatory and infectious risk …

Penile intraepithelial neoplasia: Distribution of subtypes, HPV genotypes and p16INK4a in 84 international cases

MJ Fernández-Nestosa, O Clavero, DF Sánchez… - Human Pathology, 2023 - Elsevier
There are few pathologic or molecular studies of penile precancerous lesions, and the
majority refers to lesions associated with invasive carcinomas. Penile Intraepithelial …