Dietary flavonoids alleviate inflammation and vascular endothelial barrier dysfunction induced by advanced glycation end products in vitro

Y Fu, Y Jia, Y Sun, X Liu, J Yi, S Cai - Nutrients, 2022 - mdpi.com
The aim of this study was to compare the protective effects of three dietary flavonoids
(apigenin-7-O-glucoside (A7G), isorhamnetin-3-O-rutinoside (I3R), and cyanidin-3-O …

The multifunctional roles of flavonoids against the formation of advanced glycation end products (AGEs) and AGEs-induced harmful effects

Q Zhou, KW Cheng, J Xiao, M Wang - Trends in Food Science & …, 2020 - Elsevier
Background Advanced glycation end products (AGEs) play a crucial role in the onset,
progression, and propagation of both macroangiopathy and microangiopathy complications …

Caffeic acid inhibits the formation of advanced glycation end products (AGEs) and mitigates the AGEs‐induced oxidative stress and inflammation reaction in human …

X Cao, Y Xia, M Zeng, W Wang, Y He… - Chemistry & …, 2019 - Wiley Online Library
The advanced glycation end products (AGEs) are the compounds produced by non‐
enzymatic glycation reaction of proteins and sugars, which can induce the generation of free …

6-C-(E-Phenylethenyl)-naringenin, a styryl flavonoid, inhibits advanced glycation end product-induced inflammation by upregulation of Nrf2

Q Zhou, H Xu, Y Zhao, B Liu, KW Cheng… - Journal of Agricultural …, 2022 - ACS Publications
Styryl flavonoids can be formed during the thermal processing of meats and flavonoid-
enriched foods, showing high potentials in the prevention of different diseases. In this study …

[HTML][HTML] Hesperetin, a dietary flavonoid, inhibits AGEs-induced oxidative stress and inflammation in RAW264. 7 cells

J Teng, J Li, Y Zhao, M Wang - Journal of Functional Foods, 2021 - Elsevier
Advanced glycation end products (AGEs) excessive accumulation in the body either by
exogenous intake or endogenous formation makes individuals prone to oxidative stress and …

[HTML][HTML] Anti-inflammatory effect of an apigenin-maillard reaction product in macrophages and macrophage-endothelial cocultures

Q Zhou, H Xu, W Yu, E Li, M Wang - Oxidative Medicine and Cellular …, 2019 - hindawi.com
Chronic inflammation is involved in the progression of various diseases, while dietary
flavonoids are reported to possess antioxidative and anti-inflammatory properties against …

Ferulic acid inhibits advanced glycation end products (AGEs) formation and mitigates the AGEs-induced inflammatory response in HUVEC cells

J Liu, Y He, S Wang, Y He, W Wang, Q Li… - Journal of Functional …, 2018 - Elsevier
Advanced glycation end products (AGEs) are complex and heterogeneous compounds,
which play an important role in diabetic-related vascular complications, especially in …

Chebulic acid inhibits advanced glycation end products-mediated vascular dysfunction by suppressing ROS via the ERK/Nrf2 pathway

MH Nam, W Son, SY Yang, YS Lee, KW Lee - Journal of Functional Foods, 2017 - Elsevier
Advanced glycation end-products (AGEs) considered as a fatal mediator in the diabetic
atherosclerotic pathology. In this study, we evaluated the effects of chebulic acid (CA) on anti …

Effects of flavonoids on the expression of the pro‐inflammatory response in human monocytes induced by ligation of the receptor for AGEs

SM Huang, CH Wu, GC Yen - Molecular nutrition & food …, 2006 - Wiley Online Library
Increasing evidence has shown advanced glycation end products (AGEs) receptor ligation
(RAGE) to be an important part of complex interactions of the oxidative stress and pro …

The coming age of flavonoids in the treatment of diabetic complications

T Caro-Ordieres, G Marín-Royo, L Opazo-Ríos… - Journal of clinical …, 2020 - mdpi.com
Diabetes mellitus (DM), and its micro and macrovascular complications, is one of the biggest
challenges for world public health. Despite overall improvement in prevention, diagnosis …