Sex-specific effects of ethanol consumption in older Fischer 344 rats on microglial dynamics and Aβ (1-42) accumulation
P Marsland, AS Vore, EM DaPrano, JM Paluch… - Alcohol, 2023 - Elsevier
Chronic alcohol consumption, Alzheimer's disease (AD), and vascular dementia are all
associated with cognitive decline later in life, raising questions about whether their …
associated with cognitive decline later in life, raising questions about whether their …
A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking
IR Grifasi, WA Evans, AD Rexha, LW Sako… - International review of …, 2019 - Elsevier
Alcoholism is a highly visible and prevalent issue in the United States. Although binge-
drinking is assumed to be a college-age problem, older adults (ages 65+) consume binge …
drinking is assumed to be a college-age problem, older adults (ages 65+) consume binge …
[HTML][HTML] Chronic ethanol causes persistent increases in Alzheimer's tau pathology in female 3xTg-AD mice: a potential role for lysosomal impairment
AE Tucker, CM Alicea Pauneto, AM Barnett… - Frontiers in Behavioral …, 2022 - frontiersin.org
Epidemiological studies have found that heavy alcohol use is associated with increased risk
for Alzheimer's disease (AD), with frequent drinking earlier in adulthood increasing risk. The …
for Alzheimer's disease (AD), with frequent drinking earlier in adulthood increasing risk. The …
Chronic intermittent ethanol exposure alters behavioral flexibility in aged rats compared to adult rats and modifies protein and protein pathways related to Alzheimer's …
Repeated excessive alcohol consumption increases the risk of developing cognitive decline
and dementia. Hazardous drinking among older adults further increases such …
and dementia. Hazardous drinking among older adults further increases such …
Preface: Setting the stage for understanding alcohol effects in late aging: A special issue including both human and rodent studies
It is widely recognized that people worldwide are living longer than in previous decades,
with formidable projections regarding the expansion of elderly age groups in the decades to …
with formidable projections regarding the expansion of elderly age groups in the decades to …
Aging with alcohol-related brain damage: Critical brain circuits associated with cognitive dysfunction
Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …
[HTML][HTML] Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice
SM Day, SC Gironda, CW Clarke, JA Snipes… - Neurobiology of …, 2023 - Elsevier
Epidemiological studies identified alcohol use disorder (AUD) as a risk factor for Alzheimer's
disease (AD), yet there is conflicting evidence on how alcohol use promotes AD pathology …
disease (AD), yet there is conflicting evidence on how alcohol use promotes AD pathology …
[HTML][HTML] Adolescent binge alcohol enhances early Alzheimer's disease pathology in adulthood through proinflammatory neuroimmune activation
A Barnett, E David, A Rohlman, VD Nikolova… - Frontiers in …, 2022 - frontiersin.org
Epidemiological studies suggest that heavy alcohol use early in life is associated with
increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with …
increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with …
[HTML][HTML] Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study
JW Kim, MS Byun, D Yi, JH Lee, K Ko, SY Jeon… - PLoS …, 2020 - journals.plos.org
Background An emerging body of literature has indicated that moderate alcohol intake may
be protective against Alzheimer disease (AD) dementia. However, little information is …
be protective against Alzheimer disease (AD) dementia. However, little information is …
Alcohol and Alzheimer's disease—does alcohol dependence contribute to beta-amyloid deposition, neuroinflammation and neurodegeneration in Alzheimer's disease …
A Venkataraman, N Kalk, G Sewell… - Alcohol and …, 2017 - academic.oup.com
Aims To investigate the underlying neurobiology between alcohol use, misuse and
dependence and cognitive impairment, particularly Alzheimer's disease (AD). Methods …
dependence and cognitive impairment, particularly Alzheimer's disease (AD). Methods …