A novel nanoluciferase-based system to monitor Trypanosoma cruzi infection in mice by bioluminescence imaging

E Silberstein, C Serna, SP Fragoso, R Nagarkatti… - PLoS …, 2018 - journals.plos.org
Chagas disease, caused by the intracellular protozoan Trypanosoma cruzi, affects 8–10
million people worldwide and represents a major public health challenge. There is no …

In vivo imaging of mice infected with bioluminescent Trypanosoma cruzi unveils novel sites of infection

C Henriques, A Henriques-Pons, M Meuser-Batista… - Parasites & vectors, 2014 - Springer
Background The development of techniques that allow the imaging of animals infected with
parasites expressing luciferase opens up new possibilities for following the fate of parasites …

Bioluminescent imaging of Trypanosoma cruzi infection

KV Hyland, SH Asfaw, CL Olson, MD Daniels… - International journal for …, 2008 - Elsevier
Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a
major public health problem in Central and South America. The pathogenesis of Chagas …

Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers …

AF Francisco, U Saade, S Jayawardhana… - PLoS neglected …, 2022 - journals.plos.org
Background Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is
a serious public health problem throughout Latin America. With 6 million people infected …

A New Experimental Model for Assessing Drug Efficacy against Trypanosoma cruzi Infection Based on Highly Sensitive In Vivo Imaging

MD Lewis, AF Francisco, MC Taylor… - Journal of …, 2015 - journals.sagepub.com
The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, one of the
world's major neglected infections. Although development of improved antiparasitic drugs is …

Exploiting Genetically Modified Dual-Reporter Strains to Monitor Experimental Trypanosoma cruzi Infections and Host-Parasite Interactions

MC Taylor, AF Francisco, S Jayawardhana… - T. cruzi Infection …, 2019 - Springer
Trypanosoma cruzi is the causative agent of Chagas disease, the most important parasitic
infection in Latin America. Despite a global research effort, there have been no significant …

Highly Sensitive In Vivo Imaging of Trypanosoma brucei Expressing “Red-Shifted” Luciferase

AP McLatchie, H Burrell-Saward… - PLoS neglected …, 2013 - journals.plos.org
Background Human African trypanosomiasis is caused by infection with parasites of the
Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan …

A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research

F Olmo, S Jayawardhana, AA Khan… - PLOS Neglected …, 2024 - journals.plos.org
Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that displays
considerable genetic diversity. Infections result in a range of pathological outcomes, and …

Bioluminescent imaging of Trypanosoma cruzi infection in Rhodnius prolixus

C Henriques, DP Castro, LHF Gomes, ES Garcia… - Parasites & vectors, 2012 - Springer
Background Usually the analysis of the various developmental stages of Trypanosoma cruzi
in the experimentally infected vertebrate and invertebrate hosts is based on the …

In Situ Detection of Dormant Trypanosoma cruzi Amastigotes Using Bioluminescent-Fluorescent Reporters

F Sánchez-Valdéz, A Padilla - T. cruzi Infection: Methods and Protocols, 2019 - Springer
Chagas disease agent, Trypanosoma cruzi, is capable to persist after prolonged drug
treatment using effective drugs. The reason of treatment failure is not known, but recent …