▪ Objective: To compare the effects of atenolol and nifedipine on mood and cognitive
function in elderly hypertensive patients.▪ Design: Randomized, double-blind, crossover …

Study objective: To test reports that beta blockers, particularly lipopbilic forms, impair
cognitive function and cause psychiatric disturbances. Design: Randomized, double-blind …

• This double-blind, three-way crossover study measured the influence of β-blocker
treatment on drowsiness and mental test performance in older hypertensive patients and …

OBJECTIVES: Hypertension is associated with impaired cognition, but it is unclear whether
this impairment is reversible. We sought to evaluate the effect of blood pressure reduction on …

Background: Little information has been published on the impact of antihypertensive
medications on quality of life in older persons. Particular concern has existed that lowering …

All antihypertensive treatments, including placebo, are associated with cognitive side effects.
These side effects are rarely clear-cut and involve mood, quality of sleep, daytime sedation …

We conducted a multicenter, randomized, double-blind, parallel group trial to compare the
impact of titrated doses of atenolol (50 to 100 mg once a day), enalapril (5 to 20 mg once a …

The prevalence and incidence of degenerative and vascular dementias increase
exponentially with age, from 70 years onward. In view of the increasing longevity of humans …

THE BENEFITS of treating older patients with systolic hypertension have become well
known since the completion of the Sys-tolic Hypertension in the Elderly Program (SHEP), 1 a …

This study was designed to determine whether blood pressure reduction, per se, causes
adverse effects on cognitive and behavioral function in elderly hypertensive patients. Men …