[HTML][HTML] Retinoblastoma: An update on genetic origin, classification, conventional to next-generation treatment strategies

A Pareek, D Kumar, A Pareek, MM Gupta, P Jeandet… - Heliyon, 2024 - cell.com
The most prevalent paediatric vision-threatening medical condition, retinoblastoma (RB),
has been a global concern for a long time. Several conventional therapies, such as systemic …

[HTML][HTML] Retinoblastoma: A review of the molecular basis of tumor development and its clinical correlation in shaping future targeted treatment strategies

S Rathore, A Verma, R Ratna, N Marwa… - Indian Journal of …, 2023 - journals.lww.com
Retinoblastoma is a retinal cancer that affects children and is the most prevalent intraocular
tumor worldwide. Despite tremendous breakthroughs in our understanding of the …

Emerging therapeutic targets for retinoblastoma

R Manukonda, RVL Narayana, S Kaliki… - Expert Opinion on …, 2022 - Taylor & Francis
ABSTRACT Introduction Retinoblastoma (Rb) is an early childhood intraocular tumor of the
retina and is managed by multimodal therapeutic approaches. Recent advanced targeted …

Frontiers in the management of retinoblastoma

P Lin, JM O'Brien - American journal of ophthalmology, 2009 - Elsevier
PURPOSE: To provide an overview of the current clinical management of retinoblastoma by
discussing the trends in the categorization, treatment, and recent advances in molecular …

[HTML][HTML] New horizons in retinoblastoma treatment: an updated review article

F Azimi, R Mirshahi, M Naseripour - Molecular Vision, 2022 - ncbi.nlm.nih.gov
Retinoblastoma (Rb) is a rare childhood intraocular malignancy with an incidence rate of
approximately 9000 children per year worldwide. The management of Rb is inherently …

[HTML][HTML] Retinoblastoma: present scenario and future challenges

VV Byroju, AS Nadukkandy, M Cordani… - Cell Communication and …, 2023 - Springer
With an average incidence of 1 in every 18,000 live births, retinoblastoma is a rare type of
intraocular tumour found to affect patients during their early childhood. It is curable if …

Retinoblastoma: an overview

A Ray, DS Gombos - The Indian Journal of Pediatrics, 2012 - Springer
Retinoblastoma, the most common intraocular malignancy of childhood arises due to
mutation of the retinoblastoma gene on chromosome 13q14. In the hereditary setting this …

Update on the Treatment of Retinoblastoma

M Manrique, D Akinbolue, WP Madigan… - NeoReviews, 2021 - publications.aap.org
Retinoblastoma (Rb) is the most common pediatric ocular malignancy and accounts for 2%
of all childhood cancers. Rb is initiated by a mutation of the RB 1 tumor suppressor gene …

[HTML][HTML] Retinoblastoma: etiology, modeling, and treatment

R Kaewkhaw, D Rojanaporn - Cancers, 2020 - mdpi.com
Retinoblastoma is a retinal cancer that is initiated in response to biallelic loss of RB1 in
almost all cases, together with other genetic/epigenetic changes culminating in the …

Lessons from retinoblastoma: implications for cancer, development, evolution, and regenerative medicine

MA Dyer - Trends in molecular medicine, 2016 - cell.com
Retinoblastoma is a rare childhood cancer of the developing retina, and studies on this
orphan disease have led to fundamental discoveries in cancer biology. Retinoblastoma has …