[HTML][HTML] Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management

DK Taylor, K Holthouser, JH Segars, PC Leppert - F1000Research, 2015 - ncbi.nlm.nih.gov
Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female
reproductive tract, but there are few non-surgical treatment options. Although many …

[HTML][HTML] Human myometrial and uterine fibroid stem cell-derived organoids for intervening the pathophysiology of uterine fibroid

S Banerjee, W Xu, I Chowdhury, A Driss, M Ali… - Reproductive …, 2022 - Springer
Uterine fibroids (UFs)(leiomyomas or myomas) are the most common clonal neoplasms of
the uterus in women of reproductive age worldwide. UFs originate from myometrium consist …

Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics

MS Islam, A Ciavattini, F Petraglia… - Human reproduction …, 2018 - academic.oup.com
BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

[HTML][HTML] Uterine fibroids (leiomyomas): Epidemiology, clinical features, diagnosis, and natural history

EA Stewart, SK Laughlin-Tommaso, D Levine - UpToDate. Mar, 2019 - medilib.ir
INTRODUCTION—Uterine leiomyomas (also referred to as fibroids or myomas) are the most
common pelvic neoplasm in females [1, 2]. They are noncancerous monoclonal tumors …

Epigenetic and genetic landscape of uterine leiomyomas: a current view over a common gynecological disease

AS Laganà, D Vergara, A Favilli, VL La Rosa… - Archives of gynecology …, 2017 - Springer
Purpose Despite the numerous studies on the factors involved in the genesis and growth of
uterine leiomyomas, the pathogenesis of these tumors remains unknown. Intrinsic …

Possible involvement of inflammatory/reparative processes in the development of uterine fibroids

O Protic, P Toti, MS Islam, R Occhini… - Cell and tissue …, 2016 - Springer
Uterine leiomyomas are benign tumors in the smooth muscle layer of the uterus. The most
common histological type is the “usual leiomyoma”, characterized by overexpression of ECM …

Leiomyoma: genetics, assisted reproduction, pregnancy and therapeutic advances

G Levy, MJ Hill, S Beall, SM Zarek, JH Segars… - Journal of assisted …, 2012 - Springer
Purpose Uterine leiomyomas are common, benign, reproductive tract tumors affecting a
majority of reproductive aged women. They are associated with gynecologic morbidity and …

A comprehensive review of the pharmacologic management of uterine leiomyoma

TD Lewis, M Malik, J Britten… - BioMed research …, 2018 - Wiley Online Library
Uterine leiomyomata are the most common benign tumors of the gynecologic tract impacting
up to 80% of women by 50 years of age. It is well established that these tumors are the …

Hormones and pathogenesis of uterine fibroids

FM Reis, E Bloise, TM Ortiga-Carvalho - Best Practice & Research Clinical …, 2016 - Elsevier
Highlights•Both estradiol and progesterone are essential for uterine fibroid
development.•Ovarian blockade arrests leiomyoma growth, but it has many side …

Uterine fibroids: the role of signaling pathways in the pathogenesis. A literature review

MI Yarmolinskaya, NI Polenov… - Journal of obstetrics …, 2020 - journals.eco-vector.com
Uterine fibroids are one of the most common benign tumors of the female reproductive
system, originating from smooth muscle cells of the cervix or uterine body. The controversial …