Antibodies to oxidized low density lipoprotein: epidemiological studies and potential clinical applications in cardiovascular disease.

P Gounopoulos, E Merki, LF Hansen… - Minerva …, 2007 - europepmc.org
The pathogenesis of atherosclerosis is mediated by genetic susceptibility along with a
variety of cardiovascular risk factors and environment influences. As atherosclerotic lesions …

Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease

T Lehtimäki, S Lehtinen, T Solakivi… - … , and vascular biology, 1999 - Am Heart Assoc
Oxidation of low density lipoproteins (LDL) obviously plays an important role in the
pathogenesis of atherosclerosis. The purpose of the study was to determine whether …

Humoral immune response against defined oxidized low-density lipoprotein antigens reflects structure and disease activity of carotid plaques

I Gonçalves, MLM Gronholdt, I Söderberg… - … , and vascular biology, 2005 - Am Heart Assoc
Background—Immune responses against oxidized low-density lipoprotein (LDL) play an
important role in atherosclerosis. The aim of this study was to investigate if humoral immune …

Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis

W Palinski, JL Witztum - Journal of internal medicine, 2000 - Wiley Online Library
Palinski W, Witztum JL (University of California San Diego, La Jolla, California, USA).
Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the …

Associations between autoantibodies against apolipoprotein B-100 peptides and vascular complications in patients with type 2 diabetes

GN Fredrikson, DV Anand, D Hopkins, R Corder, R Alm… - Diabetologia, 2009 - Springer
Aims/hypothesis Oxidation of LDL in the arterial extracellular matrix is a key event in the
development of atherosclerosis and autoantibodies against oxidised LDL antigens reflect …

Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study

M Mayr, S Kiechl, S Tsimikas, E Miller, J Sheldon… - Journal of the American …, 2006 - jacc.org
Objectives: We investigated whether associations exist between immune reactions to
oxidized low-density lipoproteins (OxLDLs), chronic infections, and carotid atherosclerosis …

Oxidized LDL antibodies in treatment and risk assessment of atherosclerosis and associated cardiovascular disease

J Nilsson, G Nordin Fredrikson… - Current …, 2007 - ingentaconnect.com
Immune responses against oxidized forms of LDL play a critical role in activation and
regulation of the inflammatory process that characterizes all stages of atherosclerosis. In …

Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis

A Schiopu, J Bengtsson, I Söderberg… - Circulation, 2004 - Am Heart Assoc
Background—Accumulation and oxidation of LDL are believed to be important initiating
factors in atherosclerosis. Oxidized LDL is recognized by the immune system, and animal …

Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin …

AE Fraley, GG Schwartz, AG Olsson, S Kinlay… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to define the relationship between oxidative biomarkers,
cardiovascular disease (CVD) risk factors, and inflammatory and thrombosis biomarkers …

A role for autoantibodies in atherogenesis

RA Iseme, M McEvoy, B Kelly, L Agnew… - Cardiovascular …, 2017 - academic.oup.com
An increased risk of cardiovascular disease (CVD) has long been recognized amongst
people with autoimmune disease. It has been unclear whether this is due mainly to the …