Oxidized low density lipoproteins: the bridge between atherosclerosis and autoimmunity. Possible implications in accelerated atherosclerosis and for immune …

CF Suciu, M Prete, P Ruscitti, E Favoino… - Autoimmunity …, 2018 - Elsevier
Atherosclerotic vasculopathy is a multifactorial process causing vessels damage and
cardiovascular diseases, the leading causes of death worldwide. Atherosclerotic plaque is …

Immunogenic oxidized low-density lipoprotein/β2-glycoprotein I complexes in the diagnostic management of atherosclerosis

LR Lopez, K Kobayashi, Y Matsunami… - Clinical reviews in allergy …, 2009 - Springer
Oxidized low-density lipoprotein (oxLDL) promotes atherosclerosis through a complex
interaction of inflammatory and immunologic factors that lead to macrophage lipid uptake …

The effects of lipid-lowering therapy on low-density lipoprotein auto-antibodies: relationship with low-density lipoprotein oxidation and plasma total antioxidant status

C Örem, A Örem, HA Uydu, S Çelik, C Erdöl… - Coronary artery …, 2002 - journals.lww.com
Background Oxidized low-density lipoprotein (Ox-LDL) is believed to play an important role
in the progression of atherosclerosis. Oxidative modification of low-density lipoprotein (LDL) …

Antibodies to oxidized LDL in atherosclerosis development—clinical and animal studies

J Hulthe - Clinica chimica acta, 2004 - Elsevier
Atherosclerotic lesions represent the principal cause of death in western industrialized
countries. Immune mechanisms have been suggested to play a key role in the development …

[HTML][HTML] IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem …

VJ van den Berg, DO Haskard, A Fedorowski… - …, 2018 - thelancet.com
Abstract Background Certain immunoglobulins (Ig) are proposed to have protective
functions in atherosclerosis. Objectives We tested whether serum levels of IgG and IgM …

Oxidized low density lipoprotein and innate immune receptors

YI Miller, MK Chang, CJ Binder, PX Shaw… - Current opinion in …, 2003 - journals.lww.com
Oxidized low density lipoprotein and innate immune receptors : Current Opinion in
Lipidology Oxidized low density lipoprotein and innate immune receptors : Current Opinion …

Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis

O McLeod, A Silveira, GN Fredrikson, K Gertow… - Atherosclerosis, 2014 - Elsevier
Objective Experimental studies have suggested that autoimmunity is involved in
atherosclerosis and provided evidence that both protective and pro-atherogenic immune …

Role of the adaptive immune system in atherosclerosis

K Ley - Biochemical Society Transactions, 2020 - portlandpress.com
Atherosclerosis, the pathology underlying heart attacks, strokes and peripheral artery
disease, is a chronic inflammatory disease of the artery wall initiated by elevated low-density …

Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor–deficient mice with increased atherosclerosis

W Palinski, RK Tangirala, E Miller… - … , and vascular biology, 1995 - Am Heart Assoc
Increasing evidence indicates that immune processes modulate atherogenesis. Oxidized
LDL (Ox-LDL) is immunogenic, and autoantibodies recognizing epitopes of Ox-LDL have …

Antibodies to Oxidized LDL in Relation to Carotid Atherosclerosis, Cell Adhesion Molecules, and Phospholipase A2

J Hulthe, O Wiklund, E Hurt-Camejo… - … , and vascular biology, 2001 - Am Heart Assoc
The role of the humoral immune response to oxidized low density lipoprotein (Ox-LDL) in
atherogenesis is unclear and available studies are contradictory. The aims of the present …