The role of oxidized low-density lipoprotein (ox-LDL) in the pathogenesis of atherosclerosis
has been the object of intense investigation. It has been proposed that, due to the antigenic …

The sequestering of oxidation-modified low-density lipoprotein by macrophages results in
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …

Current strategies for prevention of cardiovascular disease focus on risk factor intervention.
Although these have been proven both safe and effective results from randomized clinical …

Background Antibody antioxidized low density lipoproteins (oxLDL) might play a role both in
atherogenesis and in the pathogenesis of acute coronary syndromes. Methods and Results …

Objective—Labeled oxidation-specific antibodies (Ox-AB) detect, quantify, and
noninvasively image lipid-rich atherosclerotic lesions. However, it is unknown whether Ox …

Higher cardiovascular morbidity in patients with a wide range of autoimmune diseases
highlights the importance of autoimmunity in promoting atherosclerosis. Our purpose was to …

Accumulating evidence suggests that oxidation-specific epitopes (OSEs) constitute a novel
class of damage-associated molecular patterns (DAMPs) generated during high oxidative …

Background: The relationship between autoantibodies against human oxidized low-density
lipoprotein (anti-oxLDL) and the progression of atherosclerotic diseases is unclear. This …

Aims Antibodies to oxidized low-density lipoproteins (oxLDLAbs) are detectable in the
serum of patients with and without atherosclerosis, but it is unclear if they play a pathogenic …

Objectives HLA-DRB1 is associated with an increased risk of cardiovascular disease in
patients with rheumatoid arthritis (RA). This study aimed to determine the effect of HLA …