The malaria parasite Plasmodium possesses a relict, non-photosynthetic plastid known as
the apicoplast. The apicoplast is essential for parasite survival, and harbors several plant …

Intracellular parasites of the phylum Apicomplexa harbor a plastid-like organelle called
apicoplast that is the most reduced organelle of this type known. Due to the medical …

Development of effective therapies for intracellular eukaryotic pathogens is a serious
challenge, given the protected location of these pathogens and the similarity of their biology …

The malaria parasite harbours an indispensable plastid known as the 'apicoplast'. The
apicoplast's exact role remains uncertain, but it houses components involved in fatty acid …

Fatty acids are essential components of membranes, and are also involved in cell signalling.
Plasmodium, the parasite that causes malaria, scavenges fatty acids from its hosts …

Lipid flipping in the membrane bilayers is a widespread eukaryotic phenomenon that is
catalyzed by assorted P4-ATPases. Its occurrence, mechanism, and importance in …

Toxoplasma gondii possesses sphingolipid synthesis capabilities and is equipped to
salvage lipids from its host. The contribution of these two routes of lipid acquisition during …

Toxoplasma gondii is an obligate intracellular parasite that contains a relic plastid, called the
apicoplast, deriving from a secondary endosymbiosis with an ancestral alga. Metabolic …

New chemotherapies for human and animal apicomplexan infections are needed as a
component of future strategies to deal with these diseases. An extensive search for new …

Apicomplexan parasitic diseases impose devastating impacts on much of the world's
population. The increasing prevalence of drug resistant parasites and the growing number …