Increased alpha-fetoprotein serum level is predictive for survival and recurrence of hepatocellular carcinoma in non-cirrhotic livers

CDM Witjes, WG Polak, C Verhoef, FALM Eskens… - Digestive surgery, 2013 - karger.com
Background: Hepatocellular carcinoma (HCC) may be diagnosed in the absence of
cirrhosis. However, little is known about prognostic factors for the survival of HCC patients …

Changes of serum alpha-fetoprotein and alpha-fetoprotein-L3 after hepatectomy for hepatocellular carcinoma: prognostic significance

XF Zhang, ZF Yin, K Wang, ZQ Zhang, HH Qian… - … & Pancreatic Diseases …, 2012 - Elsevier
Background Alpha-fetoprotein (AFP) is the most established tumor marker of hepatocellular
carcinoma (HCC), but one of its limitations is non-specificity. Many studies have …

Significance of alpha‐fetoprotein levels for detection of early recurrence of hepatocellular carcinoma after hepatic resection

K Shirabe, K Takenaka, T Gion… - Journal of surgical …, 1997 - Wiley Online Library
Background The recurrence of hepatocellular carcinoma (HCC) after surgery is common.
The present study was conducted in order to clarify the significance of alpha‐fetoprotein …

The prognostic utility of baseline alpha‐fetoprotein for hepatocellular carcinoma patients

JP Silva, RA Gorman, NG Berger, S Tsai… - Journal of Surgical …, 2017 - Wiley Online Library
Introduction Alpha‐fetoprotein (AFP) has a valuable role in postoperative surveillance for
hepatocellular carcinoma (HCC) recurrence. The utility of pretreatment or baseline AFP …

Selective prognostic impact of serum α-fetoprotein level in patients with hepatocellular carcinoma: Analysis of 543 patients in a single center

TI Huo, YH Huang, WY Lui, JC Wu… - Oncology …, 2004 - spandidos-publications.com
The prognostic impact of serum α-fetoprotein (AFP) level in patients with hepatocellular
carcinoma (HCC) is controversial. This study aimed to investigate the predictive ability of …

Changes in highly sensitive alpha‐fetoprotein for the prediction of the outcome in patients with hepatocellular carcinoma after hepatectomy

H Toyoda, T Kumada, T Tada, T Ito, A Maeda… - Cancer …, 2014 - Wiley Online Library
We investigated changes in highly sensitive lens culinaris agglutinin A‐reactive fraction of
alpha‐fetoprotein (hsAFP‐L3) measured using a novel method and its predictive ability for …

Alpha fetoprotein changes predict hepatocellular carcinoma survival beyond the Milan criteria after hepatectomy

J Shen, C Li, T Wen, L Yan, B Li, W Wang… - Journal of Surgical …, 2017 - Elsevier
Background Assessing the outcomes of surgeries for hepatocellular carcinoma (HCC)
patients who exceed the Milan criteria is necessary. Some studies have demonstrated that …

Serum alpha-fetoprotein level per tumor volume reflects prognosis in patients with hepatocellular carcinoma after curative hepatectomy.

T Furihata, T Sawada, J Kita, Y Iso, M Kato… - Hepato …, 2008 - europepmc.org
Results No significant correlation between serum AFP levels and presence of cirrhosis or
ICGR15 was observed. A significant correlation existed between serum AFP levels and both …

Postoperative α-fetoprotein response predicts tumor recurrence and survival after hepatectomy for hepatocellular carcinoma: a propensity score matching analysis

XL Li, XD Zhu, H Cai, Y Li, J Zhou, J Fan, ZY Tang… - Surgery, 2019 - Elsevier
Background To investigate the prognostic values of the change of α-fetoprotein within 1
week after resection of hepatocellular carcinoma. Methods We retrospectively analyzed …

New nomogram predicts the recurrence of hepatocellular carcinoma in patients with negative preoperative serum AFP subjected to curative resection

W Gan, JL Huang, MX Zhang, YP Fu… - Journal of surgical …, 2018 - Wiley Online Library
Background There is currently no established model for predicting the recurrence of
hepatocellular carcinoma (HCC) in patients with negative alpha‐fetoprotein (AFP) after …