Disturbed zinc (Zn) homeostasis in mammals is mainly characterized by impaired bone
generation accompanied with growth retardation. However, the underlying mechanisms that …

Zinc (Zn) deficiency syndrome, discovered only half a century ago, first showed the
physiological significance of this trace mineral. More recent studies have shown that a …

Zinc (Zn) supplementation stimulates bone growth in Zn-deficient humans and animals. A
biphasic pattern of mineralization has been observed in cultured osteoblasts; an initiation …

Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

Zinc is an essential micronutrient that plays critical roles in numerous physiological
processes, including bone homeostasis. The majority of zinc in the human body is stored in …

Zinc has become a prominent nutrient of clinical and public health interest in the new
millennium. Functions and actions for zinc emerge as increasingly ubiquitous in mammalian …

More than five decades ago, Dr. Ananda S. Prasad discovered zinc (Zn) as the essential
trace element for human life. Zn deficiency was the first discovery in Zn imbalance-related …

Abstract Zinc (Zn2+) is the most abundant trace element in cells and is essential for a vast
number of catalytic, structural, and regulatory processes. Mounting evidence indicates that …

Zinc is an essential mineral that is required for normal skeletal growth and bone
homeostasis. Furthermore, zinc appears to be able to promote bone regeneration. However …