Temporal and intensity coding of pain in human cortex
CA Porro, V Cettolo… - Journal of …, 1998 - journals.physiology.org
Porro, Carlo A., Valentina Cettolo, Maria Pia Francescato, and Patrizia Baraldi. Temporal
and intensity coding of pain in human cortex. J. Neurophysiol. 80: 3312–3320, 1998. We …
and intensity coding of pain in human cortex. J. Neurophysiol. 80: 3312–3320, 1998. We …
Multiple brain networks mediating stimulus–pain relationships in humans
The brain transforms nociceptive input into a complex pain experience comprised of
sensory, affective, motivational, and cognitive components. However, it is still unclear how …
sensory, affective, motivational, and cognitive components. However, it is still unclear how …
Altered excitability and local connectivity of mPFC-PAG neurons in a mouse model of neuropathic pain
J Cheriyan, PL Sheets - Journal of Neuroscience, 2018 - Soc Neuroscience
The medial prefrontal cortex (mPFC) plays a major role in both sensory and affective aspects
of pain. There is extensive evidence that chronic pain produces functional changes within …
of pain. There is extensive evidence that chronic pain produces functional changes within …
Corticostriatal regulation of acute pain
E Martinez, HH Lin, H Zhou, J Dale, K Liu… - Frontiers in cellular …, 2017 - frontiersin.org
The mechanisms for acute pain regulation in the brain are not well understood. The
prefrontal cortex (PFC) provides top-down control of emotional processes, and it projects to …
prefrontal cortex (PFC) provides top-down control of emotional processes, and it projects to …
Molecular, circuit, and anatomical changes in the prefrontal cortex in chronic pain
The brain integrates information about the intensity, quality, and location of noxious inputs
with other states such as attention, anxiety, fear, and expectation. A key brain region where …
with other states such as attention, anxiety, fear, and expectation. A key brain region where …
Different brain circuitries mediating controllable and uncontrollable pain
Uncontrollable, compared with controllable, painful stimulation can lead to increased pain
perception and activation in pain-processing brain regions, but it is currently unknown which …
perception and activation in pain-processing brain regions, but it is currently unknown which …
Dual and opposing functions of the central amygdala in the modulation of pain
TD Wilson, S Valdivia, A Khan, HS Ahn, AP Adke… - Cell reports, 2019 - cell.com
Pain perception is essential for survival and can be amplified or suppressed by
expectations, experiences, and context. The neural mechanisms underlying bidirectional …
expectations, experiences, and context. The neural mechanisms underlying bidirectional …
[HTML][HTML] Brain oscillations differentially encode noxious stimulus intensity and pain intensity
Noxious stimuli induce physiological processes which commonly translate into pain.
However, under certain conditions, pain intensity can substantially dissociate from stimulus …
However, under certain conditions, pain intensity can substantially dissociate from stimulus …
Brain circuits for pain and its treatment
Pain is a multidimensional experience with sensory-discriminative, affective-motivational,
and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering …
and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering …
Brain mechanisms of pain affect and pain modulation
P Rainville - Current opinion in neurobiology, 2002 - Elsevier
Recent animal studies reveal ascending nociceptive and descending modulatory pathways
that may contribute to the affective–motivational aspects of pain and play a critical role in the …
that may contribute to the affective–motivational aspects of pain and play a critical role in the …