Interleukin-4 Gene Polymorphisms in Romanian Patients with Inflammatory Bowel Diseases: Association with Disease Risk and Clinical Features

EM Ionescu, AO Olteanu, CG Tieranu, LO Popa… - Diagnostics, 2023 - mdpi.com
1. Introduction. Multiple cytokines have been studied for their role in the propagation of the
inflammatory process related to inflammatory bowel diseases (IBD), but the role of …

Interleukin-4 and interleukin-10 gene polymorphisms in patients with inflammatory bowel disease

N Ebrahimi Daryani, A Saghazadeh… - Immunological …, 2017 - Taylor & Francis
Background: Changes in cytokine expression have been frequently found in patients with
inflammatory bowel disease (IBD). Cytokine values outside the normal range may be …

Interleukin-1 single nucleotide polymorphisms as risk factors for susceptibility of inflammatory bowel disease: an Iraqi Arab population-based study

AH Ad'hiah, EB Hessan, BA Shahab - Alexandria Journal of …, 2019 - Taylor & Francis
Objectives: It is aimed to determine the association between four single-nucleotide
polymorphisms (SNPs) of IL1 genes (rs1800587: IL1A− 889 C/T, rs16944: IL1B− 511 T/C …

Interleukin 10 promoter region polymorphisms in inflammatory bowel disease in Tunisian population

R Marrakchi, A Moussa, S Ouerhani, K Bougatef… - Inflammation …, 2009 - Springer
Objective: To test whether IL-10 promoter region polymorphisms are associated with
susceptibility to inflammatory bowel disease, we examined the contribution of interleukin-10 …

IL-1β-511 and IL-1RN* 2 polymorphisms in inflammatory bowel disease: An Italian population study and meta-analysis of European studies

VD Corleto, C Pagnini, G Margagnoni… - Digestive and Liver …, 2010 - Elsevier
BACKGROUND: Several studies have tried to find possible associations between genetic
polymorphisms and inflammatory bowel disease prevalence and/or phenotype. Our …

The polymorphism rs3024505 (C/T) downstream of the IL10 gene is associated with Crohn's disease in Serbian patients with inflammatory bowel disease

D Mijac, IV Petrovic, S Djuranovic, V Perovic… - The Tohoku Journal of …, 2016 - jstage.jst.go.jp
Inflammatory bowel disease (IBD), manifesting as Crohn's disease (CD) and ulcerative
colitis (UC), is characterized by recurring episodes of inflammation in gastrointestinal tract, in …

Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population

M Lappalainen, L Halme, U Turunen… - Inflammatory bowel …, 2008 - academic.oup.com
Background Crohn's disease (CD) and ulcerative colitis (UC), 2 major forms of inflammatory
bowel disease (IBD), are complex disorders with significant genetic predisposition. The first …

Significance of IL-1RA Polymorphism in Iranian Patients with Inflammatory Bowel Disease

NE Daryani, M Sadr, S Moossavi, S Shahkarami… - Digestive Diseases and …, 2015 - Springer
Abstract Background and Aim Interleukin (IL)-1 family members play an important role in the
pathogenesis of inflammatory bowel disease (IBD). There are conflicting results regarding …

[PDF][PDF] Interactions among interleukin-6, C-reactive protein and interleukin-6 (-174) G/C polymorphism in the pathogenesis of Crohn's disease and ulcerative colitis

B Takač, S Mihaljević, L Glavaš-Obrovac, A Kibel… - Acta Clinica …, 2020 - hrcak.srce.hr
Inflammatory bowel diseases are multifactorial disorders the clinical manifestation of which
depends on the interaction among immune response, genetic and environmental factors …

IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease

BP Gonçalves, T Flauzino, CJ Inoue… - International Journal of …, 2021 - Springer
Purpose The aim of the present study was to evaluate the IL6− 174 G> C (rs1800795) and−
572 G> C (rs1800796) genetic variants and their association with inflammatory bowel …