Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease
JL Hoffman, S Faccidomo, M Kim, SM Taylor… - International review of …, 2019 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that represents the
most common cause of dementia in the United States. Although the link between alcohol …
most common cause of dementia in the United States. Although the link between alcohol …
Alcohol as a modifiable risk factor for alzheimer's disease—evidence from experimental studies
DV Chandrashekar, RA Steinberg, D Han… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
cognitive impairment and memory loss. Epidemiological evidence suggests that heavy …
cognitive impairment and memory loss. Epidemiological evidence suggests that heavy …
[HTML][HTML] Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice
SM Day, SC Gironda, CW Clarke, JA Snipes… - Neurobiology of …, 2023 - Elsevier
Epidemiological studies identified alcohol use disorder (AUD) as a risk factor for Alzheimer's
disease (AD), yet there is conflicting evidence on how alcohol use promotes AD pathology …
disease (AD), yet there is conflicting evidence on how alcohol use promotes AD pathology …
Adolescent binge alcohol enhances early Alzheimer's disease pathology in adulthood through proinflammatory neuroimmune activation
A Barnett, E David, A Rohlman, VD Nikolova… - Frontiers in …, 2022 - frontiersin.org
Epidemiological studies suggest that heavy alcohol use early in life is associated with
increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with …
increased risk for Alzheimer's disease (AD). However, mechanisms connecting AD with …
Alcohol and Alzheimer's disease—does alcohol dependence contribute to beta-amyloid deposition, neuroinflammation and neurodegeneration in Alzheimer's disease …
A Venkataraman, N Kalk, G Sewell… - Alcohol and …, 2017 - academic.oup.com
Aims To investigate the underlying neurobiology between alcohol use, misuse and
dependence and cognitive impairment, particularly Alzheimer's disease (AD). Methods …
dependence and cognitive impairment, particularly Alzheimer's disease (AD). Methods …
Aging with alcohol-related brain damage: Critical brain circuits associated with cognitive dysfunction
Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …
[HTML][HTML] Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study
JW Kim, MS Byun, D Yi, JH Lee, K Ko, SY Jeon… - PLoS …, 2020 - journals.plos.org
Background An emerging body of literature has indicated that moderate alcohol intake may
be protective against Alzheimer disease (AD) dementia. However, little information is …
be protective against Alzheimer disease (AD) dementia. However, little information is …
Ethanol alters APP processing and aggravates Alzheimer-associated phenotypes
D Huang, M Yu, S Yang, D Lou, W Zhou, L Zheng… - Molecular …, 2018 - Springer
The majority of Alzheimer's disease (AD) cases are sporadic with unknown causes. Many
dietary factors including excessive alcohol intake have been reported to increase the risk to …
dietary factors including excessive alcohol intake have been reported to increase the risk to …
Cognitive decline and recovery in alcohol abuse
CJ Perry - Journal of molecular neuroscience, 2016 - Springer
Alcohol consumption triggers a neuroinflammatory response which, if prolonged, can lead to
substantial volume loss in both gray and white matter. This brain injury is associated with …
substantial volume loss in both gray and white matter. This brain injury is associated with …
[HTML][HTML] Autophagy alleviates ethanol-induced memory impairment in association with anti-apoptotic and anti-inflammatory pathways
Y Liu, Y Zhang, J Peng, H Wang, X Li, X Li… - Brain, Behavior, and …, 2019 - Elsevier
Chronic excessive drinking leads to a wide spectrum of neurological disorders, including
cognitive deficits, such as learning and memory impairment. However, the neurobiological …
cognitive deficits, such as learning and memory impairment. However, the neurobiological …