The injured spinal cord: imaging, histopathologic, clinical correlates, and basic science approaches to enhancing neural function after spinal cord injury

RM Quencer, RP Bunge - Spine, 1996 - journals.lww.com
In 50 postmortem injured cords that we have examined with detailed magnetic resonance
imaging (MRI) and histopathologic analysis, a number of new and clinically important …

The unique histopathological responses of the injured spinal cord: implications for neuroprotective therapy

L Guth, Z Zhang, O Steward - Annals of the New York Academy …, 1999 - Wiley Online Library
Tissue destruction at the primary site of a spinal cord injury leads to persistent necrosis that
progressively enlarges the lesion. Steroids attenuate this necrotizing process and promote …

MR-imaging of chronic spinal cord injury. Association with neurologic function

A Nidecker, M Kocher, M Maeder, O Gratzl, GA Zäch… - Neurosurgical …, 1991 - Springer
Twenty-two para-and tetraplegic patients with chronic spinal cord injuries were examined
with magnetic resonance imaging (MRI). The clinical course in the entire rehabilitation …

Endogenous recovery of injured spinal cord: longitudinal in vivo magnetic resonance imaging

PA Narayana, RJ Grill, T Chacko… - Journal of neuroscience …, 2004 - Wiley Online Library
Pathological changes were followed longitudinally with in vivo magnetic resonance imaging
(MRI) and behavioral studies in experimental spinal cord injury (SCI). MRI‐observed …

Diagnosis and management of spinal cord trauma.

JE Wilberger - Journal of Neurotrauma, 1991 - europepmc.org
New information on MRI findings after acute spinal cord injury, changing concepts on the
timing of surgical intervention, and a clearer understanding of the pathophysiology of this …

Human spinal cord retains substantial structural mass in chronic stages after injury

MH TUSZYNSKI, K GABRIEL, K GERHARDT… - Journal of …, 1999 - liebertpub.com
In chronic stages of human spinal cord injury, atrophy of the cord has been reported in
regions both at and distant to the injury site. Local cord atrophy results from the direct effects …

Histological and ultrastructural analysis of white matter damage after naturally‐occurring spinal cord injury

PM Smith, ND Jeffery - Brain pathology, 2006 - Wiley Online Library
Detailed analysis of the structural changes that follow human clinical spinal cord injury is
limited by difficulties in achieving adequate tissue fixation. This study bypasses this obstacle …

Vascular mechanisms in the pathophysiology of human spinal cord injury

CH Tator, I Koyanagi - Journal of neurosurgery, 1997 - thejns.org
✓ Vascular injury plays an important role in the primary and secondary injury mechanisms
that cause damage to the acutely traumatized spinal cord. To understand the …

Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Spinal cord injury: review of basic and applied research

JC De La Torre - Spine, 1981 - journals.lww.com
This review examines, in a condensed manner, many of the major achievements related to
spinal cord injury research during the last quarter century. Most of the advances have been …