Cigarette smoke causes follicle loss in mice ovaries at concentrations representative of human exposure

AM Tuttle, M Stämpfli, WG Foster - Human Reproduction, 2009 - academic.oup.com
BACKGROUND Cigarette smoke is a documented reproductive toxicant associated with
infertility and ovarian failure. However, the underlying mechanism (s) regulating the toxic …

Cigarette smoke exposure leads to follicle loss via an alternative ovarian cell death pathway in a mouse model

AM Gannon, MR Stämpfli, WG Foster - Toxicological Sciences, 2012 - academic.oup.com
Cigarette smoking among reproductive-aged women is increasing worldwide. Cigarette
smoking is a lifestyle behavior associated with important adverse health effects including …

Scrambled and fried: cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress

AP Sobinoff, EL Beckett, AG Jarnicki… - Toxicology and applied …, 2013 - Elsevier
Cigarette smoke is a reproductive hazard associated with pre-mature reproductive
senescence and reduced clinical pregnancy rates in female smokers. Despite an increased …

Ovotoxicity of cigarette smoke: A systematic review of the literature

MC Budani, GM Tiboni - Reproductive toxicology, 2017 - Elsevier
This study reviews the scientific literature on the noxious effects of cigarette smoke on the
ovarian follicle, and the cumulative data on the impact of smoking on in vitro fertilization (IVF) …

Through the smoke: use of in vivo and in vitro cigarette smoking models to elucidate its effect on female fertility

NJ Camlin, EA McLaughlin, JE Holt - Toxicology and applied pharmacology, 2014 - Elsevier
A finite number of oocytes are established within the mammalian ovary prior to birth to form a
precious ovarian reserve. Damage to this limited pool of gametes by environmental factors …

Maternal smoke exposure impairs the long-term fertility of female offspring in a murine model

NJ Camlin, AP Sobinoff, JM Sutherland… - Biology of …, 2016 - academic.oup.com
The theory of fetal origins of adult disease was first proposed in 1989, and in the decades
since, a wide range of other diseases from obesity to asthma have been found to originate in …

Follicle growth is inhibited by benzo-[a]-pyrene, at concentrations representative of human exposure, in an isolated rat follicle culture assay

MS Neal, J Zhu, AC Holloway… - Human Reproduction, 2007 - academic.oup.com
BACKGROUND The adverse effects of cigarette smoking on human fertility have been well
documented. However, the mechanism (s) underlying the detrimental effects of cigarette …

[HTML][HTML] Cigarette smoke impairs granulosa cell proliferation and oocyte growth after exposure cessation in young Swiss mice: an experimental study

LLO Paixão, RP Gaspar-Reis, GPL Gonzalez… - Journal of ovarian …, 2012 - Springer
Background Cigarette smoke is associated with decreased female fertility, causing damage
to ovarian function and disturbing follicle development. However, the effects of cigarette …

[HTML][HTML] Cigarette smoke condensate exposure delays follicular development and function in a stage-dependent manner

JC Sadeu, WG Foster - Fertility and sterility, 2011 - Elsevier
Objective To determine the effects of cigarette smoke condensate (CSC) on follicular
development and function from the early preantral stage through ovulation. Design …

Nicotine does not affect vascularization but inhibits growth of freely transplanted ovarian follicles by inducing granulosa cell apoptosis

R Bordel, MW Laschke, MD Menger… - Human …, 2006 - academic.oup.com
BACKGROUND: There is clear support for an association between smoking and decreased
female fecundity and fertility. Cigarette smoke appears to have adverse effects along a …