Genome-wide mapping studies have provided evidence of a type 1 diabetes susceptibility
gene (IDDM8) that is located on chromosome 6q27. However, association studies of IDDM8 …

Recently, several studies have demonstrated that tumor necrosis factor microsatellite
polymorphism (TNFa) contributes to the susceptibility of type 1 diabetes. This study …

The IDDM5 gene, which is identified by whole-genome searches, is located on chromosome
6q25. TAB2 (MAP3K7IP2 [mitogen-activating protein kinase kinase kinase 7 interacting …

We conducted a genome-wide association study of type 2 diabetes (T2D) using 459,359
SNPs in a Japanese population with a three-stage study design (stage 1, 4,470 cases and …

Genome scans in families with type 2 diabetes identified a putative locus on chromosome
20q. For this study, linkage disequilibrium mapping was used in an effort to narrow a 7.3-Mb …

To replicate the recent finding of a type 2 diabetes locus (NIDDM2) on 12q, families
segregating early-onset autosomal-dominant type 2 diabetes were screened for linkage …

Aims/hypothesis In order to identify type 2 diabetes disease susceptibility gene (s) in a
Japanese population, we applied a region-wide case–control association test to the 20.4 Mb …

To identify a novel susceptibility locus for type 2 diabetes, we performed an imputation-
based, genome-wide association study (GWAS) in a Japanese population using newly …

Type 1 Diabetes Mellitus is a complex and polygenic disease due to gene-environment
interactions. The role of genetic background of diabetes has been extensively investigated …

A possible pathogenic mutation in the Β 3-adrenergic-receptor gene (Trp64Arg) has been
reported to be associated with an earlier age of onset of non-insulin-dependent diabetes …