Catharanthus roseus (Madagascar periwinkle), a medicinal plant possessing high
pharmacological attributes, is widely recognized for the biosynthesis of anticancer …

With over 3000 reported structures, monoterpenoid indole alkaloids (MIAs) constitute one of
the largest alkaloid groups in nature, including the clinically important anticancer drug …

Catharanthus roseus synthesizes one of the most structurally, chemically and biologically
active phytomolecules monoterpenoids indole alkaloids (MIAs) with having a wide range of …

As the only source for the low-abundance antitumor agents vinblastine and vincristine,
Catharanthus roseus is highly valued for its diversity of more than 130 monoterpenoid indole …

The development of various plant-based engineering efforts has been facilitated by recent
large-scale transcriptomic resources. In consideration of the progress in the study of …

Simple Summary Plants produce very diverse chemicals that are used for the treatment of
human ailments. However, plants tend to produce these high-value compounds in small …

As the only source for the low-abundance antitumor agents vinblastine and vincristine,
Catharanthus roseus is highly valued and has been studied extensively as a model for …

The Madagascar periwinkle [Catharanthus roseus (L.) G. Don] is a plant species known for
its production of TIAs (terpenoid indole alkaloids), many of which are pharmaceutically …

Plant specialized metabolites are widely used in the pharmaceutical industry, including the
monoterpene indole alkaloids (MIAs) vinblastine and vincristine, which both display …

Monoterpene indole alkaloids (MIAs) have important therapeutic value, including as
anticancer and antimalarial agents. Because of their chemical complexity, therapeutic MIAs …