Objective The efficacy of glucosamine sulfate (GS) in the symptomatic treatment of patients
with osteoarthritis (OA) is suggested to be mediated by still unknown effects on the altered …

Several clinical studies demonstrated that glucosamine sulfate (GS) is effective in controlling
osteoarthritis (OA), showing a structure‐modifying action. However, little is known about the …

Glucosamine sulfate is able to stimulate proteoglycan synthesis by chondrocytes and has
mild anti-inflammatory properties. In clinical trials, glucosamine sulfate was more effective …

OBJECTIVE: To study the effects of oral glucosamine sulfate on the development of
osteoarthritis (OA) and to examine concomitant changes in the nociceptive behavior of rats …

OBJECTIVE: To investigate the effects of glucosamine (GlcN) on chondrocyte proliferation,
matrix production, and gene expression for providing insights into the biochemical basis of …

Objective Glucosamine sulphate has been shown in a large double-blind, placebo-
controlled clinical trial to prevent structural damage and improve clinical symptoms of …

Objective: The functional integrity of articular cartilage is determined by a balance between
chondrocyte biosynthesis of extracellular matrix and its degradation. In osteoarthritis (OA) …

Objective To determine whether oral glucosamine alleviates cartilage degradation in an
animal model of osteoarthritis (OA). Methods The effect of 8 weeks of daily oral glucosamine …

Glucosamine sulfate is a controversial osteoarthritis remedy that is presumed to stimulate
articular cartilage glycosaminoglycan synthesis by increasing glucosamine concentrations …

Osteoarthritis (OA) affects a large segment of the aging population and is a major cause of
pain and disability. At present, there is no specific treatment available to prevent or retard the …