Cytotoxic human CD4+ T cells
PJ van de Berg, EM van Leeuwen, IJ Ten Berge… - Current opinion in …, 2008 - Elsevier
The induction of adaptive immune responses critically depends on helper signals provided
by CD4+ T cells. These signals not only license antigen presenting cells (APC) to activate …
by CD4+ T cells. These signals not only license antigen presenting cells (APC) to activate …
The activation of the adaptive immune system: cross-talk between antigen-presenting cells, T cells and B cells
The adaptive immune system consists of T and B cells that express clonally distributed
antigen receptors. To achieve functional adaptive immune responses, antigen-specific T cell …
antigen receptors. To achieve functional adaptive immune responses, antigen-specific T cell …
Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll‐like receptors in immunity
V Lampropoulou, E Calderon‐Gomez… - Immunological …, 2010 - Wiley Online Library
B lymphocytes contribute to immunity through production of antibodies, antigen presentation
to T cells, and secretion of cytokines. B cells are generally considered in autoimmune …
to T cells, and secretion of cytokines. B cells are generally considered in autoimmune …
Cutting edge: dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo
C Kurts, M Cannarile, I Klebba… - The Journal of …, 2001 - journals.aai.org
The mechanism of cross-presentation enables professional APCs to induce CD8 T cell-
mediated immune responses against exogenous Ags. Through this mechanism, APCs can …
mediated immune responses against exogenous Ags. Through this mechanism, APCs can …
New insights into B cells as antigen presenting cells
Highlights•The MHCII antigen presentation pathway has unique features in B cells.•The
MHCII antigen presentation pathway is regulated differently in different B cell subsets.•B cell …
MHCII antigen presentation pathway is regulated differently in different B cell subsets.•B cell …
[HTML][HTML] B cells promote CD8 T cell primary and memory responses to subunit vaccines
The relationship between B cells and CD4 T cells has been carefully studied, revealing a
collaborative effort in which B cells promote the activation, differentiation, and expansion of …
collaborative effort in which B cells promote the activation, differentiation, and expansion of …
CD8α− dendritic cells induce antigen-specific T follicular helper cells generating efficient humoral immune responses
Recent studies on T follicular helper (Tfh) cells have significantly advanced our
understanding of T cell-dependent B cell responses. However, little is known about the early …
understanding of T cell-dependent B cell responses. However, little is known about the early …
Toll-like receptor 2-mediated human B cell differentiation
LM Ganley-Leal, X Liu, LM Wetzler - Clinical immunology, 2006 - Elsevier
Human B cells likely have a major role in the adjuvant activity of Toll-like receptor (TLR) 9
agonists by enhancing innate and adaptive immune responses. As several TLR2 ligands …
agonists by enhancing innate and adaptive immune responses. As several TLR2 ligands …
Activation of B cells by non‐canonical helper signals
A Cerutti, M Cols, I Puga - EMBO reports, 2012 - embopress.org
Cognate interaction between T and B lymphocytes of the adaptive immune system is
essential for the production of high‐affinity antibodies against microbes, and for the …
essential for the production of high‐affinity antibodies against microbes, and for the …
Regulation of T follicular helper cell formation and function by antigen presenting cells
CD4+ T cells can differentiate into numerous subsets characterized by expression of a suite
of cytokines and effector molecules that endow them with specialized functions. By …
of cytokines and effector molecules that endow them with specialized functions. By …