Methodology of predicting novel key regulators in ovarian cancer network: a network theoretical approach
Background Identification of key regulator/s in ovarian cancer (OC) network is important for
potential drug target and prevention from this cancer. This study proposes a method to …
potential drug target and prevention from this cancer. This study proposes a method to …
Integrated bioinformatic analysis identifies networks and promising biomarkers for hepatitis B virus‐related hepatocellular carcinoma
Y Ji, Y Yin, W Zhang - International Journal of Genomics, 2020 - Wiley Online Library
Chronic infection with hepatitis B virus (HBV) has long been recognized as a dominant
hazard factor for hepatocellular carcinoma (HCC) and accounts for at least half of HCC …
hazard factor for hepatocellular carcinoma (HCC) and accounts for at least half of HCC …
Identification of human disease genes from interactome network using graphlet interaction
Identifying genes related to human diseases, such as cancer and cardiovascular disease,
etc., is an important task in biomedical research because of its applications in disease …
etc., is an important task in biomedical research because of its applications in disease …
[HTML][HTML] Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus
Z Li, J Xu, H Cui, J Song, J Chen, J Wei - Medicine, 2020 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) accounts for up to 90% of all primary hepatic
malignancies; it is the sixth most common cancer and the second most common cause of …
malignancies; it is the sixth most common cancer and the second most common cause of …
A multi-method approach for proteomic network inference in 11 human cancers
Y Şenbabaoğlu, SO Sümer… - PLoS computational …, 2016 - journals.plos.org
Protein expression and post-translational modification levels are tightly regulated in
neoplastic cells to maintain cellular processes known as 'cancer hallmarks'. The first Pan …
neoplastic cells to maintain cellular processes known as 'cancer hallmarks'. The first Pan …
[HTML][HTML] Introducing crucial protein panel of gastric adenocarcinoma disease
M Rezaei-Tavirani, M Rezaei-Tavirani… - … and Hepatology from …, 2017 - ncbi.nlm.nih.gov
Aim: Since interactome analysis of diseases can provide candidate biomarker panel related
to the diseases, in this research, protein-protein interaction (PPI) network analysis is used to …
to the diseases, in this research, protein-protein interaction (PPI) network analysis is used to …
Graph-theoretical comparison reveals structural divergence of human protein interaction networks
ME Futschik, A Tschaut, G Chaurasia… - Genome Informatics, 2007 - jstage.jst.go.jp
Protein interactions constitute the backbone of the cellular machinery in living systems. Their
biological importance has led to systematic assemblies of large-scale protein-protein …
biological importance has led to systematic assemblies of large-scale protein-protein …
Prognostic genes of hepatocellular carcinoma based on gene coexpression network analysis
B Xu, W Lv, X Li, L Zhang, J Lin - Journal of cellular …, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common subtype in liver cancer whose
prognosis is affected by malignant progression associated with complex gene interactions …
prognosis is affected by malignant progression associated with complex gene interactions …
Computational discovery of Epstein-Barr virus targeted human genes and signalling pathways
S Mei, K Zhang - Scientific reports, 2016 - nature.com
Epstein-Barr virus (EBV) plays important roles in the origin and the progression of human
carcinomas, eg diffuse large B cell tumors, T cell lymphomas, etc. Discovering EBV targeted …
carcinomas, eg diffuse large B cell tumors, T cell lymphomas, etc. Discovering EBV targeted …
A computational method based on the integration of heterogeneous networks for predicting disease-gene associations
The identification of disease-causing genes is a fundamental challenge in human health
and of great importance in improving medical care, and provides a better understanding of …
and of great importance in improving medical care, and provides a better understanding of …