The generation of an effective immune response against an infection while also limiting
tissue damage requires a delicate balance between pro-and anti-inflammatory responses …

IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …

Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …

Macrophages play a central role in infections, as a target for pathogens and in activation of
the immune system. Interleukin-10 (IL-10), a cytokine produced by macrophages, is a potent …

Recent studies have documented that the immunoregulatory functions of IL-12 may play a
role in promoting endogenous protective responses during infections and/or contribute to …

Abstract Interleukin-10 (IL-10) is recognized as an anti-inflammatory cytokine that
downmodulates inflammatory immune responses at multiple levels. In innate cells …

Interleukin-12 is a cytokine produced by antigen-presenting cells that is essential for host
defense against intracellular microbial infection and control of malignancy by virtue of its …

Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …

Macrophage effector functions are essential for clearing mycobacterial infections. Interleukin
10 (IL-10) negatively regulates macrophages and could be a factor inhibiting effective …

The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …