Ergosterone has been proved to have potential antitumor effect on H22 tumor-bearing mice,
but the antitumor mechanism and key regulators are still unclear. The current study was …

Background Stigmasterol (SS) has been proven to possess potential anticancer activities in
several cancer cell lines, but its molecular mechanism is still unknown. Thus, we …

Background The treatment of non-small cell lung cancer (NSCLC) is challenging due to
immune tolerance and evasion. Salidroside (SAL) is an extract in traditional Chinese …

Salidroside inhibited the proliferation of cancer cell. Nevertheless, the mechanism has not
been completely clarified. The purpose of the study is to explore the mechanisms of …

Triptolide, the main active ingredient in Tripterygium wilfordii Hook. f.(Celastraceae), has
shown promising effects against a variety of tumors. However, the molecular …

Rottlerin as a natural agent, which is isolated from Mallotus philippinensis, has been
identified to play a critical role in tumor inhibition. However, the molecular mechanism of …

Salidroside is a natural product of phenols with a wide range of pharmacological functions,
but whether it plays a role in regulating autophagy is unclear. We systematically investigated …

Abstract Treatment with ergolide, a sesquiterpene lactone from Inula britannica var
chinensis, caused the induction of apoptosis in Jurkat T cells, which was confirmed by DNA …

Ethnopharmacological relevance Inula oculus christi belongs to the family of Asteraceae
and it was traditionally wide used in treatment of kidney stones and urethra infection; …

Persistent activation of signal transducer and activator of transcription 3 (STAT3) is one of
the characteristic features of renal cell carcinoma (RCC) and often linked to its deregulated …